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Completed

NCT Number: NCT02013739

Description of Insulin Resistance in Patients With Chronic Heart Failure

The purpose of this study is to describe insulin resistance in a general chronic heart failure population, in combination with muscle strength, body composition and cardiac function.

It is assumed that insulin resistance is increased in CHF patient, and that this is related to decreased muscle strength and decreased lean tissue mass.

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Key information

Conditions

Chronic Heart Failure

Sex eligibility

All sexes

Study type

Observational

Primary location

Hasselt University

Hasselt, Limburg, 3500, Belgium

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • diagnosis of chronic heart failure for at least 6 months,
  • clinically stable (not hospitalized) for more than 3 months prior to the onset of the study,

Exclusion criteria

  • glucose lowering medical therapy

Treatment and study plan

Primary outcomes

  1. Glucose tolerance

    Time frame: day1

    glucose and insulin concentration measurements in blood during oral glucose tolerance test

Secondary outcomes

  1. HbA1c, blood lipids, BNP

    Time frame: day 1

  2. Muscle strength: maximal strength tested on a isokinetic dynamometer

    Time frame: Day 1

  3. Body composition: dual energy x-ray absorptiometry

    Time frame: Day 1

  4. cardiac function: echocardiography, retrospective from hospital files

    Time frame: retrospective

  5. Health-related quality of life: MLHFQ and Eq5d

    Time frame: Day 1

Sponsors and collaborators

Lead sponsor

Hasselt University

Other

Registry information

Official study title

Description of Insulin Resistance and Explanatory Variables in Patients With Chronic Heart Failure

Important dates

Study start
2011
Primary completion
2012
Study completion
2013
First posted
Dec 17, 2013
Registry last updated
Dec 17, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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