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OpenTrials
Completed

NCT Number: NCT06135519

Dermogenesis With Mesenchymal Stem Cells

Dermogenesis With Mesenchymal Stem Cells in treating Post Acne Depressed Spots

Completed

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Key information

Conditions

Dermal Regeneration

Age range

Up to 50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

King Edward Medical University

Lahore, Punjab Province, 54000, Pakistan

About this study

management at two different stages of the course of the disease. First one at the stage of active disease which needs cleansers, antibiotics, retinoids, anti inflammatory agents and hormonal manipulation. Once active disease is over, patients report to clinician with depressed spots which are caused by localized dermal disruption and fat atrophy post inflammation or spontaneous epithelial rupture or scratching by the patient. These acne spots are hard to treat due to many reasons. Firstly, excision is difficult as size of most of them is small and they are in a large in number. Secondly, filling with and without subcision is not adequately addressing the deformity. Currently, a combination of filling with synthetic filler or fat and resurfacing by peeling, LASER or dermabrasion is in practice. In-spite of all, a treatment is still required to address post acne spots (Ice Spec Spots) adequately.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Acne spots

Exclusion criteria

  • Active acne

Treatment and study plan

Autologous Mesenchymal stem cells injection

Procedure

Autologous Mesenchymal stem cells will be seperated from harvested fat and injected in acne scars

Homogenized fat injection

Procedure

Autologous fat will be harvested, homogenized and injected.

Primary outcomes

  1. Dermal thickness

    Time frame: 3 months

    on microscopy of biopsy section

Sponsors and collaborators

Lead sponsor

King Edward Medical University

Other

Registry information

Official study title

Dermogenesis With Mesenchymal Stem Cells: A Fabulous Remedy For Post Acne Depressed Spots

Acronym: MSCs

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Nov 18, 2023
Registry last updated
Mar 7, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.