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OpenTrials
Completed

NCT Number: NCT05630144

Deprescribing for Older Adults After Hospital Discharge in Home Health Care

The purpose of this study is to examine the feasibility of providing a medication optimization program to improve patient health outcomes during the transition from hospital to home. This is because the period after hospital discharge is critical to long-term recovery, overall quality of life, and prevention of future hospitalizations.

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Key information

Conditions

Polypharmacy

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Rochester Medical Center

Rochester, New York, 14642, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Patient Inclusion Criteria:

  • 65 years of age and older
  • currently hospitalized or having been hospitalized in the previous 2 weeks
  • having a discharge disposition of home with a referral to receive HHC services from URMHC, or currently receiving HHC services from URMHC
  • taking more than 10 regular medications daily
  • having a primary care provider who is in the URMC system
  • Ability to self-consent
  • English-speaking

Patient Exclusion Criteria:

  • end-of-life prognosis in the following 6 months
  • currently receiving hospice care, end-of-life care, or palliative care
  • conditions that impact the receipt of the intervention, such as severe cognitive impairment that interferes with the subject's ability to communicate with interventionists;
  • substantial difficulties in hearing, vision, and verbal expression that disable the participant from communicating effectively while receiving the HomeMed intervention

Treatment and study plan

HomeMed

Behavioral

The HomeMed intervention is a multidisciplinary deprescribing intervention including home visits and team-based telehealth communication (optional). The components included in the HomeMed intervention include home medication review, medication education and provision of tools to assist the patients with medication administration, assessment of deprescribing targets by a trained geriatric clinical pharmacist, communication with the patient's treating primary care provider about deprescribing recommendation, deprescribing implementation (optional), and deprescribing monitoring (optional). Depending on the patient's treating primary care provider's decision on deprescribing and monitoring, the number of home visits ranges from a minimum of three to more with the entire duration of the intervention ranging from approximately 1 to 3 months.

Primary outcomes

  1. mean time spent on intervention

    Time frame: 3 months

  2. number of participants who complete a post intervention survey about feasibility

    Time frame: 3 months

  3. Percentage of participants undergoing deprescribing

    Time frame: 3 months

  4. Percentage of intervention adherence indicators checked

    Time frame: 3 months

  5. Percentage of patients who improve in ability to do things that are important before and after intervention

    Time frame: 3 months

  6. Total number of medications used per participant

    Time frame: 3 months

  7. Percentage of patients who report a reduction in medication burden

    Time frame: 3 months

    Medication burden will be reported by phone or survey.

  8. Percentage of participants who report a reduction in medication side effect

    Time frame: 3 months

    Side effects will be collected by phone.

Sponsors and collaborators

Lead sponsor

University of Rochester

Other

Collaborators

  • National Institute on Aging (NIA)

Registry information

Official study title

Deprescribing for Older Adults After Hospital Discharge in Home Health Care - A Pilot Feasibility Study of the HomeMed Deprescribing Intervention

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Nov 29, 2022
Registry last updated
Jul 16, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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