FAR Oral and Systemic Health Consulting, Inc
Costa Mesa, California, 92627, United States
NCT Number: NCT07738198
The objective of this study is to assess clinical efficacy of a toothpaste containing stannous fluoride (Colgate-Palmolive Company, New York, NY, USA) to provide dental hypersensitivity relief (tactile and air blast) in comparison to commercially available potassium-based desensitizing toothpaste (Senodyne Extra Whitening Toothpaste, GasoSmithKline Co., UK) and commercially available non-desensitizing toothpaste (Colgate Cavity Protection Toothpaste, Colgate-Palmolive Company, New York, NY, USA) over a seven day study period
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Notify Me18 year–70 year
All sexes
Interventional
Phase 3
Costa Mesa, California, 92627, United States
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Be anterior to the molars and demonstrating dentin exposure due to cervical erosion/abrasion or gingival recession.
Have a qualifying dentin hypersensitivity response to tactile stimuli applied to the cervical surface (gingivo-facial 1/3) as defined by a response score between 10-50grams of force (Yeaple Probe, XiniX Research Inc. Portsmouth, NH, USA).
-Have a qualifying dentin hypersensitivity response to air blast stimuli applied for one second to the cervical surface (gingivo-facial 1/3) as defined by a score of 2 or 3 on the Schiff Cold Air Sensitivity Scale
Exclusion criteria
brush twice daily (morning and evening) Duration of exposure: one (1) minute
Brush twice daily (morning and evening) Duration of exposure: one (1) minute
Brush twice daily (morning and evening) Duration of exposure: one (1) minute
Time frame: baseline, 1 day, 3 day, 7 day
Tactile sensitivity will be assessed by use of Sensing Probe Yeaple Electronic Force Sensing Probe, Model 200A. Sensitivity will be defined by a score in the range of 10-50 gms. of force.
Time frame: baseline, 1 day, 3 day, 7 day
The air will be directed at the exposed buccal surface of the sensitive tooth air delivered by a standard dental unit syringe at a measured temperature of 19-21°C (70°F[± 3°F].
Colgate Palmolive
Industry
Dentin Hypersensitivity Reduction Efficacy of a Dentifrice Containing Stannous Fluoride as Compared to Commercially-available Potassium-based Desensitizing Toothpaste.
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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