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NCT Number: NCT06920017

Demographic Data and Clinical Presentation of Pediatric Uveitis

To describe and analyze the demographics, Clinical characteristics, etiology, and visual outcomes of pediatric uveitis cases attending the outpatient clinic of Ophthalmology department, Assiut University Hospital.

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Key information

Conditions

Age range

Up to 18 year

Sex eligibility

All sexes

Study type

Observational

About this study

Uveitis is a form of eye inflammation that affects the middle layer of tissue in the eye wall (uvea).

It is the third leading cause of blindness worldwide .Uveitis is more common in adults; however, children comprise 2.2% to 21.6% of patients in various studies.Despite a lower incidence of uveitis in children, the rate of visual loss may be worse than that of adults . The onset of uveitis in children is often insidious and is only discovered during routine screening.The lack of significant symptoms and delayed presentation to an ophthalmologist leads to morbidity and a decrease in visual acuity . The length of time between the diagnosis of uveitis and the referral to a tertiary eye center is strongly correlated with the complications rate and degree of visual impairment.

Uveitis is classified according to the International Uveitis Study Group criteria based on the anatomical location of the inflammation and is categorized as anterior, intermediate, Posterior or panuveitis. It is also described based on clinical onset, duration and course.

Some uveitis syndromes are unique to children, such as juvenile idiopathic arthritis (JIA), Kawasaki syndrome, Familial Juvenile Systemic Granulomatosis and Tubulointerstitial Nephritis-Uveitis syndrome. Other conditions are more prevalent in the pediatric population due to environmental factors such as trematode induced uveitis.

Due to the lack of epidemiological studies on the demographic and Clinical Characteristics of pediatric uveitis in Upper Egypt. This study aims to improve diagnosis, management, and treatment strategies tailored to the population.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Uveitis patients <18 years old
  • must be able to participate in the study.

Exclusion criteria

  • Age over 18 years.
  • Patients with post pentrating ocular trauma.
  • Patients whose legal guardians are unwilling to participate in the study.

Treatment and study plan

Primary outcomes

  1. Distribution of uveitis subtypes.

    Time frame: Baseline

  2. Differences by age, gender, or ethnicity.

    Time frame: Baseline

  3. Prevalence of systemic associations.

    Time frame: Baseline

  4. Prevalence of Visual outcomes.

    Time frame: Baseline

  5. Prevalence of complications rate.

    Time frame: Baseline

Study contacts

Contact information is provided by the study sponsor or research team.

Hasnaa Salah Ebrahim Abo Elyuon, master

CONTACT

[email protected]

+201090793398

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Demographic Data and Clinical Presentation of Pediatric Uveitis Patients in Upper Egypt.

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Apr 9, 2025
Registry last updated
Apr 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.