Low fermentable substrate diet
OtherDiet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols.
NCT Number: NCT01339117
The purpose of this study is to determine whether a specific diet may help children with irritable bowel syndrome.
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Notify Me7 year–17 year
All sexes
Interventional
Not applicable
Children's Nutrition Research Center, Houston, Texas, United States
Many children experience stomach pain or discomfort at some point during their lives. Some children have belly discomfort frequently while others rarely have this problem. There have been very few studies to test treatments for recurrent stomach discomfort in children. Recently, studies in adults with recurrent stomach discomfort suggest that diet changes may help. Currently, we do not know if these same diets will work in children with the same problem.
In this study, two different diets will be provided (delivered) for two days with at least 5 days in between each provided diet. The child's symptoms will be recorded over the two days of each diet. Children will be asked to capture samples of their breath during the last day of the each two day delivered diet. Stool samples will also be collected.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Must include all of the following:
Exclusion criteria
Will include any of the following:
Diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols.
Diet high in fermentable oligosaccharides, disaccharides, monosaccharides and polyols
Time frame: 9 days (2 dietary intervention periods)
Comparisons of abdominal pain frequency (number of abdominal pain episodes per day) will be made between each two day dietary period spanning a 9 days.
Time frame: 9 days (2 dietary intervention periods)
The severity of abdominal pain episodes will be measured on a 1-10 (10 being most severe) ordinal scale. Average severity per abdominal pain episode during each two day dietary period will be compared over 9 days.
Time frame: 9 days (2 dietary intervention periods)
Daily hydrogen gas production (parts per million) will be compared between each 2 day dietary intervention period over 9 days.
Baylor College of Medicine
Other
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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