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Completed

NCT Number: NCT06146348

Deimplementing CXR After CVC (DRAUP) in the ICU

This study proposes adapting and testing an innovative, behavioral theory-driven deimplementation program called DRAUP in two intensive care units for proof of concept and support that the program can help providers and hospital organizations address context determinants of deimplementation. Study data will be used to optimize the intervention for a subsequent larger trials.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Washington University School of Medicine

St Louis, Missouri, 63108, United States

About this study

There are millions of critically ill patients annually who require imaging confirmation after central venous catheter insertion. Emerging literature demonstrates that ultrasound is a faster alternative to historical chest xray, thus serving as the ideal confirmation for catheter use. When able to confirm catheter position, ultrasound decreases the number of unnecessary chest radiographs, cumulative resources (technologist, radiologist, equipment), and patient care delays. However, providers are not adopting this practice. Previously, we developed and initiated a successful evidence-based deimplementation program for ultrasound in lieu of chest xray called DRAUP in the Emergency Department. We now move to adapt the deimplementation bundle in the new environment of the Intensive Care Unit (ICU) with hopeful continued success.

In experiment 1, qualitative analysis will be employ a systematic approach to DRAUP component refinement dosed to the unique context of the Intensive Care Unit and implementation outcomes as well as cost will be evaluated. In experiment 3, mixed methods will be used to evaluate the mechanism of impact of the refined program in the new environment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

-Measure the effectiveness and cost effectiveness of DRAUP on discontinuation of CXRs

Inclusion criteria

for DRAUP training:

(1) ICU faculty, fellows, senior residents (post graduate year 3) and advanced practice practitioners

  • ICU inclusion for DRAUP program:
  • Availability of ultrasound machines with archiving capability (DICOM)
  • A minimum of 100 supradiaphragmatic CVC insertions annually in adult patients (age >18)
  • Capacity to access digital archiving (PICOM)
  • Patient inclusion for DRAUP program:
  • supradiaphragmatic CVC placed
  • Patient exclusion for DRAUP program:
  • severe instability (cardiac arrest, severe shock) where CVC would be used without CXR,
  • level 1 trauma;
  • burn patients with no viable skin surface for imaging

Treatment and study plan

adapted DRAUP strategy bundle

Behavioral

DRAUP deimplementation strategy bundle includes: 1) education and training, 2) supervision and in-person decision support, and 3) audit and feedback to target capability. Opportunity is addressed by 4) algorithm development and 5) organizational support. Finally, 6) facilitators and 7) planned adaptation after interval program assessment address the motivations needed to change behavior.

Primary outcomes

  1. DRAUP in

    Time frame: 24 months

    Deadoption of CXR after US guided CVC confirmation

Secondary outcomes

  1. Fidelity

    Time frame: 24 months

    Percentage of DRAUP non-adherence

Sponsors and collaborators

Lead sponsor

Washington University School of Medicine

Other

Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

Registry information

Official study title

Adapting and Testing a Deimplementation Program in the Intensive Care Unit

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Nov 24, 2023
Registry last updated
Apr 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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