Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality

Identify the best combination of predictive variables that influence ionizing radiation dose and improved image quality through analysis and quantification of PET-CT images in simulators and patients.

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Key information

Conditions

Malignant Neoplasm of Breast Breast Diseases Breast Neoplasms Colonic Diseases Colonic Neoplasms Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Hemic and Lymphatic Diseases Hodgkin Disease Immune System Diseases Immunoproliferative Disorders Intestinal Diseases Intestinal Neoplasms Lymphatic Diseases Lymphoma Lymphoma, Non-Hodgkin Lymphoproliferative Disorders Malignant Melanoma of the Skin Malignant Neoplasm of Bronchus and Lung Malignant Neoplasm of Colon Malignant Neoplasm of Small Intestine Neoplasms Neoplasms by Histologic Type Neoplasms by Site Non-Hodgkin Lymphoma, Follicular (Nodular) Secondary Neoplasm Malignant and Unspecified Lymph Nodes Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Hospital Sao Rafael

Salvador, Estado de Bahia, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Healthy volunteers;
Both genders;
Age over 18 years;
Clinical indication for PET-CT scan.

Exclusion criteria

Pregnant women;
Patients who have lesions in the liver metabolically active whether primary or metastatic;
Patients with movement difficulties.

Treatment and study plan

Image quantify

Other

Will be observed all patients who perform PET / CT examinations, independent of clinical indication, in nuclear medicine at Hospital Sao Rafael. Those who show interest in participating in the study, will be provided free and informed consent form (ICF) for your appreciation. This evaluation will serve for analysis and quantification of PET-CT images.

Primary outcomes

Correlation of body weight with the variation coefficient (image noise).

Time frame: 360 seconds

The image noise will be measured by VOI (Volume Of Interest) in the images. The units of measure will be kilograms (kg) for body weight, and percentage for the variation coefficient.

Secondary outcomes

Correlation of dose-regimen with the variation coefficient (image noise).

Time frame: 360 seconds

The dose-regimen will be calculated based on radiation dose and body surface. The image noise will be measured by VOI (Volume Of Interest) in the images. The units of measure will be MegaBecquerel per kilogram (MBq/kg) for dose-regimen, and percentage for the variation coefficient.
Correlation of acquisition protocol time with the variation coefficient (image noise).

Time frame: 360 seconds

Images will be acquired every 30 seconds until a maximum of 360 seconds. The image noise will be measured by VOI (Volume Of Interest) in the images. The units of measure will be seconds for the acquisition time, and percentage for the variation coefficient.

Sponsors and collaborators

Lead sponsor

Hospital Sao Rafael

Other

Registry information

Acronym: pet-ct

Important dates

Study start: 2014
Primary completion: 2015
Study completion: 2016
First posted: Mar 4, 2015
Registry last updated: Nov 28, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed