UZA
Edegem, Antwerpen, 2650, Belgium
Location status: Recruiting
NCT Number: NCT06440330
The primary aim of this prospective, multicentre study is to develop an accurate and convenient tool to predict the risk of PTDM at 3 months post-transplant, based on information on the day of transplantation (day 0).
In order to create such model, we will start by identifying individual predictor variables at the day of transplantation and subsequently explore the optimal combination of these predictors in multivariable models.
Secondary objectives include:
* Compare the performance of the model based on predictor variables at day 0 with existing models for prediction of PTDM (Chakkera, San Antonio Diabetes Prediction Model and Framingham Offspring Study Diabetes Mellitus algorithm) * Explore the glucose level evolution during the first 2 weeks after transplantation using continuous glucose monitoring, and its relationship with baseline patient characteristics and immunosuppressant drug use. * Evaluate the added value of incorporating information on glucose levels in the first and second weeks post-transplant to improve the PTDM prediction model. * Identify predictors for early post-transplant hyperglycemia (first 2 weeks post-transplantation) * Explore the correlation between early post-transplant hyperglycemia (fasting glycemia, pre-dinner glycemia) and PTDM at 3 months
Interested in participating?
Request Info18 year and older
All sexes
Observational
Edegem, Antwerpen, 2650, Belgium
Location status: Recruiting
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
continuous glucose monitoring will be used during the first 14 days post-transplantation
Time frame: at 10-13 weeks post-transplantation
Post-transplant diabetes mellitus diagnosis based on the need for glucose lowering therapy or 2h-OGTT value of >=200mg/dL
Contact information is provided by the study sponsor or research team.
University Hospital, Antwerp
Other
Acronym: DECODE
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT05240274
Chronic Disease, Disease Attributes
London, United Kingdom
View Trial DetailsNCT04965935
Diabetes Mellitus, Diabetes Mellitus, Type 2
Toronto, Ontario, Canada
View Trial DetailsNCT02591849
Post-transplant Diabetes Mellitus
Oslo, Norway
View Trial DetailsNCT06538961
BK Virus Infection, Kidney Transplant; Complications
Richmond, Virginia, United States
View Trial Details