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OpenTrials
Completed

NCT Number: NCT06895876

Deep Parasternal Intercostal Plane Block

Cardiac surgery is a source of severe post operative pain witch can cause major respiratory complications due to non optimal post operative rehabilitation.

Multimodal analgesia provides acceptable pain control , but does not seem sufficient during coughing or mobilization. The use of morphine also exposes patients to side effects (nausea, vomiting, pruritus, respiratory depression, chronic pain, ileus). Bleeding and hemodynamic risks of peridural and spinal aneshesia limits their use.

The postoperative efficacy of deep parasternal intercostal plane block has not yet been evaluated sufficiently. The aim of this study is to evaluate the efficacity of TTMPB on the quality of postoperative recovery after cardiac surgery.

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Key information

Conditions

Nerve Block

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Institut Arnault Tzanck

Saint-Laurent-du-Var, 06700, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients requiring cardiac surgery with sternotomy

Exclusion criteria

  • Emergency procedure
  • Procedures requiring lateral chest drainage
  • Hemodynamic instability
  • Severe kidney or liver failure
  • BMI > 40
  • Chronic pain
  • Allergy to local anesthesics
  • Pregnant woman
  • Long term opioïds use

Treatment and study plan

Deep Parasternal Intercostal Plane Block

Procedure

The block is performed bilaterally in the 4th intercostal space. The probe is placed in the latero-median axis and a needle is placed latero-medially between the intercostal and transverse thoracic muscle. The solution is then injected under ultrasound control

Primary outcomes

  1. Quality of recovery 15 (QoR-15)

    Time frame: 24 hours after surgery

    QoR-15 score : 0 to 150. Addition of 15 items note between 0 to 10 150 = perfect post operative recovery possible 0 = worst post operative recovery possible

Secondary outcomes

  1. Total morphine consumption at 24 hours

    Time frame: 24 hours after surgery

    Total morphine consumption, in milligrams, during the first 24 hours after surgery.

Sponsors and collaborators

Lead sponsor

Institute Arnault Tzanck, France

Other

Registry information

Official study title

Deep Parasternal Intercostal Plane Block : Effect on the Quality of Postoperative Recovery After Cardiac Surgery

Acronym: DPIP

Important dates

Study start
2022
Primary completion
2022
Study completion
2025
First posted
Mar 26, 2025
Registry last updated
May 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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