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Completed

NCT Number: NCT05969418

Deep Learning Optical Coherence Tomography (OCT) and OCT Angiography (OCTA) in NVC

To evaluate the activity of neovascular macula degeneretion as assessed by SD-OCTand OCT-A using a split-person study design and deep-learning quantification.

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Key information

Conditions

Macular Degeneration Choroidal Neovascularization Choroid Diseases Choroidal Neovascularization Eye Diseases Metaplasia Neovascularization, Pathologic Pathologic Processes Pathological Conditions, Signs and Symptoms Uveal Diseases

Age range

50 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Federico II University

Naples, 80121, Italy

About this study

Exudative neovascular macular degeneration is the primarily an age-related retinal condition The optical coherence tomography angiography represents a novel and noninvasive diagnostic technique that allows a detailed and quantitative analysis of retinal and choriocapillary vascular features in order to choose the best therapy .

The study evaluates the changes in structural optical coherence tomography and optical coherence tomography angiography features in neovascular macular degeration patients undergoing ANTI-VEGF treatments using artificial intelligence.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

age older than 50 years

  • diagnosis of neovascular macular degeneration
  • absence of previous retinal surgery and congenital eye diseases.
  • absence of errors of refraction
  • absence of lens opacities
  • absence of low-quality OCT and OCTA images

Exclusion criteria

• age younger than 50 years

  • previous retinal surgery and congenital eye diseases
  • errors of refraction
  • lens opacities
  • low-quality OCT and OCTA images

Treatment and study plan

Diagnostic test: using artificial intelligence to evaluate the changes OCT and OCTA parameter

Diagnostic Test

Diagnostic test: using artificial intelligence to evaluate the changes OCT and OCTA parameter before and after ANTI-VEGF treatment

Primary outcomes

  1. The measurements of retinal and choriocapillary vessel density in patients with macular degeneration complicated by nvc

    Time frame: more than sixmonths

Sponsors and collaborators

Lead sponsor

Federico II University

Other

Registry information

Official study title

Deep Learning OCT and OCTA Quantification in Neovascular Age Related Macular Degeneration

Acronym: OCTA

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Aug 1, 2023
Registry last updated
May 22, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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