Deep Inferior Epigastric Artery Flap for Breast Reconstruction

Background: There is no consensus on the duration of prophylactic antibiotics for autologous breast reconstruction after mastectomy. We try to standardize prophylactic antibiotics use during breast reconstruction with deep inferior epigastric perforator flap following mastectomy.

Methods: This retrospective case series involved 108 patients who underwent immediate breast reconstruction with deep inferior epigastric perforator flap in Ditmanson Medical Foundation Chia-Yi Christian Hospital between 2012 and 2019. Patients were divided into three groups based on prophylactic antibiotic duration: 1 day, 3 days and >7 days for patients with drains Data were analyzed between January and April, 2021.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Breast Cancer Anti-Infectives Adverse Reaction Breast Diseases Breast Neoplasms Infections Neoplasms Neoplasms by Site Perforator Flap Skin Diseases Skin and Connective Tissue Diseases

Age range

24 year–63 year

Sex eligibility

Female

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

This retrospective study involved 108 patients who underwent immediate DIEP flap breast reconstruction after unilateral or bilateral mastectomy at the Ditmanson Medical Foundation Chia-Yi Christian Hospital between 2012 and 2019.

Exclusion criteria

Age < 20 years old.

Treatment and study plan

prophylactic antibiotics duration

Drug

Prophylactic cefazolin 1000 mg was given 30 minutes before surgery, every 4 hours in the peri-operative period, and every 6 hours in the post-operative care. Different discontinued duration of antibiotics was divided to 3 groups in one day, 3 days and until to drain removal.

Primary outcomes

surgical site infection (SSI)

Time frame: Patients were then followed up in the outpatient department for 1 year.

Infection rate of surgical wounds of breast and abdomen.

Sponsors and collaborators

Lead sponsor

Chiayi Christian Hospital

Other

Registry information

Official study title

Division of Plastic and Reconstruction Surgery

Important dates

Study start: 2011
Primary completion: 2019
Study completion: 2020
First posted: Oct 21, 2021
Registry last updated: Oct 21, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed