University of Florida
Gainesville, Florida, 32611, United States
NCT Number: NCT04581941
Deep Brain Stimulation (DBS) is an effective therapy for patients with medically refractory essential tremor. However, DBS programming is not standardized and multiple clinic visits are frequently required to adequately control symptoms. The investigators aim to longitudinally record brain signals from patients using a novel neurostimulator that can record brain signals. The investigators will correlate brain signals to clinical severity scores to identify pathological rhythms in the absence of DBS, and we will study the effects of DBS on these signals in order to guide clinical programming.
Looking for future studies?
Notify Me21 year–85 year
All sexes
Observational
Gainesville, Florida, 32611, United States
The development of newer technologies has allowed clinicians and researchers to better understand pathophysiological underpinnings of different disorders managed with neuromodulation. The is now the ability to stream brain signals from a newly FDA approved device, the Medtronic Percept. The investigators will study the longitudinal effects of DBS on the brain signals that are found to correlate with tremor severity as measured with wireless wearable sensors.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 6 months
A clinical scale of tremor severity (0-4, 0:no symptoms, 4:extreme)
University of Florida
Other
Deep Brain Stimulation Effects in Essential Tremor: Time Course of Electrophysiological Changes in Treatment
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT03027310
Basal Ganglia Diseases, Brain Diseases
Bethesda, Maryland, United States
View Trial DetailsNCT06235190
Central Nervous System Diseases, Essential Tremor
Phoenix, Arizona, United States
View Trial DetailsNCT05842434
Basal Ganglia Diseases, Brain Diseases
Boca Raton, Florida, United States
View Trial DetailsNCT03760406
Central Nervous System Diseases, Essential Tremor
Bordeaux, France
View Trial Details