Decompression of Odontogenic Cysts

The aim of this case-control study is to evaluate the effects of decompression of cystic jaw lesions by means of comparing pre- and post-decompression histologic findings.

The main question it aims to answer is:

Does decompression of cystic jaw lesions alter the histologic diagnosis?

A retrospective analysis was performed based on the comparison of initial and final histologic diagnoses of patients with an odontogenic cystic lesion, that was surgically treated with decompression followed by a definitive surgery.

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Key information

Conditions

Odontogenic Cysts Bone Cysts Cysts Cysts Dental Disease Jaw Cysts Jaw Diseases Keratocysts of the Jaw Mouth Diseases Musculoskeletal Diseases Neoplasms Pathologic Processes Pathological Conditions, Signs and Symptoms Pathology Periapical Diseases Periodontal Cyst Periodontal Diseases Radicular Cyst Stomatognathic Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

Akdeniz University

Antalya, 07070, Turkey (Türkiye)

About this study

The study included patients with a histologic diagnosis of an odontogenic cystic lesion, that was surgically treated with decompression followed by a definitive surgery. The study was carried out retrospectively by means of evaluating records, surgical and histologic reports of patients. Pre- and post-decompression histologic findings were compared in effort to understand if decompression leads to alteration in histologic character and change in diagnoses of lesions.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

To have an initial diagnosis of an odontogenic cystic jaw lesion confirmed with an incisional biopsy.
The patients must have undergone decompression and, enucleation or enucleation and peripheral ostectomy after decompression period.

Exclusion criteria

Previously treated patients
The patients with missing information in medical and/or dental records
The patients who did not adhere to follow-up protocol

Treatment and study plan

Primary outcomes

Change in histologic diagnosis following decompression (yes/no)

Time frame: A decompression period ranging between 2 and 15 months

A comparison will be made between the initial histologic diagnosis and post-decompression definitive histologic diagnosis of the cystic jaw lesions

Sponsors and collaborators

Lead sponsor

Akdeniz University

Other

Registry information

Official study title

The Effect of Decompression on Histologic Diagnoses of Cystic Jaw Lesions

Important dates

Study start: 2015
Primary completion: 2018
Study completion: 2023
First posted: Aug 5, 2024
Registry last updated: Aug 5, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed