Decompensation of Cirrhosis and Iron Metabolism

Inclusion criteria

• Age ≥ 18 years old.
• Diagnosis of cirrhosis, previously known or not, of any etiology, histologically proven or not.
• Hospitalization for acute on chronic liver failure:
• Ascites decompensation.
• Or spontaneous infection of the ascites fluid (defined as PNN > 250/mm3 of ascites).
• Or digestive hemorrhage related to portal hypertension (digestive fibroscopy showing active bleeding or stigmas of recent bleeding from esophageal and/or gastric varices).
• Or hepatic encephalopathy (clinically defined +/- increase in ammonia and/or by electroencephalogram and classified in stages according to West-Haven).
• Or hepato-renal syndrome (HRS-AKI criteria, EASL 2018).
• Or bacterial infection (defined by a bacteremia identified by at least one blood culture and/or an infectious site authenticated on imaging).
• Or Acute Alcoholic Hepatitis (histologically proven or not).
• Non-opposition of the patient, relative or legal representative.

Exclusion criteria

• Treatment with oral or intravenous iron in the month prior to hospitalization.
• Implementation of a TIPS in the month prior to admission.
• Presence of hepatocellular carcinoma with an expected survival < 3 months or any other progressive cancer.
• Adult person subject to legal protection (safeguard of justice, curatorship, guardianship), person deprived of liberty.