Decoding Chronic Pain With fMRI

Recent evidence suggests that chronic pain is associated with abnormal connectivity between brain regions associated with the processing of pain. We aim to test the diagnostic power of resting state functional magnetic resonance imaging (MRI) to diagnose patients with chronic back pain. Using new methods of image acquisition and analysis we aim to develop a computational method to correctly classify patients and matched control subjects.

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Key information

Conditions

Chronic Back Pain

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Addenbrookes Hospital

Cambridge, CB2 0QQ, United Kingdom

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

age 18-60
pain > 6months
right-handed
non-smoking
mechanical back pain

Exclusion criteria

significant neurological or psychiatric disease
major systemic illness
MRI exclusion criteria

Treatment and study plan

Primary outcomes

Functional brain connectivity

Time frame: 6 months

Assessed by fMRI

Sponsors and collaborators

Lead sponsor

University of Cambridge

Other

Registry information

Official study title

Observational Study to Determine Abnormalities in Resting State fMRI in Chronic Back Pain.

Important dates

Study start: 2013
Primary completion: 2016
Study completion: 2018
First posted: Jan 11, 2013
Registry last updated: Jun 8, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed