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OpenTrials
Completed

NCT Number: NCT05389397

De-implementation of Outdated Colonoscopy Surveillance Interval Recommendations Among Patients With Low-risk Adenomas

The purpose of this study is to compare the effectiveness of three standard of care outreach approaches (i.e., mailed letter, secure message, and telephone call) on patient adoption of the new 10-year colonoscopy surveillance interval recommendation for a random sample of health plan members who have a now-outdated 5-year surveillance interval due to a finding of 1-2 small adenomas at their prior colonoscopy. The primary study endpoint is the proportion of patients in each outreach arm who adopt the new 10-year colonoscopy surveillance interval.

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Key information

Conditions

Polyp of Colon Colonic Polyps Intestinal Polyps Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Polyps

Age range

54 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kaiser Permanente San Francisco Medical Center

San Francisco, California, 94115, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Kaiser Permanente Northern California (KPNC) membership>12 months
  • Primary medical center is either KP San Rafael, KP San Francisco, KP San Leandro, or KP Walnut Creek
  • 54-70 years of age at time of 5-year surveillance colonoscopy interval
  • A baseline colonoscopy with a finding of 1-2 small tubular adenomas and are due for their 5-year surveillance procedure in 2022
  • Average risk for CRC
  • A valid mailing address, kp.org account (i.e., KPNC's secure messaging portal), and telephone number at time of study enrollment.

Exclusion criteria

  • More than 12 months of membership prior to index colonoscopy, and indications that would make an individual above average risk for CRC, such as: adenoma with advanced histology on colonoscopy, adenoma >10 mm on colonoscopy, family history of CRC, prior history of colonoscopy, prior history of adenomas or colon polyp diagnoses, history of IBD, history of hereditary polyposis syndrome, 3 or more adenomas, adenoma 10 mm in size or greater, adenoma with advanced histology, and any sessile serrated polyp or traditional serrated adenoma

Treatment and study plan

Outreach

Behavioral

Mailed letter, secure message or telephone outreach will be used depending on arm enrolled

Primary outcomes

  1. Percentage of patients who respond with a 10-year surveillance interval change

    Time frame: 2 months following outreach intervention

Secondary outcomes

  1. Percentage of patients requesting a physician appointment

    Time frame: 2 months following outreach intervention

Sponsors and collaborators

Lead sponsor

Kaiser Permanente

Other

Registry information

Acronym: DESIRE

Important dates

Study start
2022
Primary completion
2022
Study completion
2023
First posted
May 25, 2022
Registry last updated
Sep 14, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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