Daytime Corneal Swelling During Wear of Narafilcon B Lenses

Inclusion criteria

• Be of legal age (i.e. ≥ 18 years).
• Be mentally competent, willing and able to sign a written informed consent form.
• Have contact lens distance sphere requirement in the range -1.00D to -6.00D.
• Have spectacle astigmatism <1.25D in each eye.
• Currently wear soft contact lenses (for at least 6 months prior to the trial) with documentation of current prescription.
• Have normal eyes with no evidence of abnormality or disease. For the purpose of this study a normal eye is defined as one having: i) no evidence of lid abnormality or infection; ii) no conjunctival abnormality or infection; iii) no clinically significant slit lamp findings (i.e, edema, staining, scarring, vascularization, infiltrates or abnormal opacities); iv) no other active ocular disease.

Exclusion criteria

• Required concurrent ocular medication.
• Any systemic illness which would contra-indicate lens wear or the medical treatment of which would affect vision or successful lens wear.
• Eye injury or surgery within eight weeks immediately prior to enrollment for this study.
• Abnormal lacrimal secretions.
• Pre-existing ocular irritation that would preclude contact lens fitting.
• Keratoconus or other corneal irregularity.
• Pregnancy, lactating or planning a pregnancy at the time of enrollment.
• Participation in any concurrent clinical trial.