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NCT Number: NCT00442091

Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema

Dandelion juice has been used in herbal medicine for at least 1000 years. Vesicular hand eczema is a rare, but difficult to treat, type of hand eczema. One case report has shown that ingestion of dandelion juice could induce a beneficial effect on this type of eczema. The purpose of this study is to test whether this effect can be retrieved in other patients.

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Key information

Conditions

Vesicular Palmoplantar Eczema Dermatitis Eczema Eczema, Dyshidrotic Pompholyx Skin Diseases Skin Diseases, Eczematous Skin Diseases, Vesiculobullous Skin and Connective Tissue Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Dermatology, Odense University Hospital

Odense, DK-5000, Denmark

About this study

Dandelion juice has been used in herbal medicine for at least 1000 years. One case report has shown a beneficial effect of this herbal remedy on dyshidrotic hand eczema, and the purpose of this pilot study is to test whether this effect can be retrieved in other patients.

The patients are recruited from our out-patient clinic. Only patients with negative patch tests to Compositae are offered treatment with dandelion juice for 20-30 days.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients with dyshidrotic eczema for at least 1 year and negative patch test reactions to Compositae (tested within the last 3 years) and normal renal and hepatic blood tests.

Exclusion criteria

  • Treatment with systemic steroids or other immunosuppressive/-modulating drugs, including UV therapy, within the last 3 months.
  • Pregnancy, lactation.
  • Compositae contact allergy.
  • Liver or gall bladder disease.
  • Abnormal renal or hepatic blood tests.

Treatment and study plan

dandelion juice

Drug

10 ml bid for 20-30 days

Primary outcomes

  1. Improvement in dyshidrotic hand eczema in the study period assessed by HECSI score.

    Time frame: 3-4 weeks

Secondary outcomes

  1. Improvement in dyshidrotic eczema in the study period assessed by the patient (Visual Analog Scale).

    Time frame: 3-4 weeks

Sponsors and collaborators

Lead sponsor

Odense University Hospital

Other

Registry information

Important dates

Study start
2010
Primary completion
2019
Study completion
2019
First posted
Mar 1, 2007
Registry last updated
Mar 4, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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