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NCT Number: NCT06946316

Dairy vs Plant-based Beverages for Improving Bone Health During Exercise

This study will evaluate the effects of consuming dairy milk versus two plant-based beverages (pea-based, and almond-based) after resistance training sessions (3 times per week for 12 months) on bone properties (bone mineral density, bone geometry), body composition, strength, and functional performance in post-menopausal women and men 50y and older.

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

College of Kinesiology University of Saskatchewan

Saskatoon, Saskatchewan, S7K 2X2, Canada

Location status: Recruiting

Location contact

Philip Chilibeck, PhD

CONTACT

[email protected]

3062303849

About this study

The purpose of the study is to compare consumption of dairy milk (1% chocolate milk) to plant-based beverages (protein-matched pea beverage and low-protein almond beverage) after resistance-training sessions on bone mineral density, bone geometric properties, lean tissue and fat mass, muscular strength, and functional performance. One-hundred and fifty postmenopausal women and men 50y or older will be randomized to one of three groups: 1) Dairy milk; 2) pea-beverage; 3) almond beverage. The study will be double-blind, accomplished by chocolate flavoring of each beverage. Participants will do supervised strength-training sessions three times per week for 12 months. After each strength-training session, participants will consume 375 ml of their beverage and then consume 375 ml of their beverage again one hour later.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women need to be postmenopausal (no age limit)
  • Men need to be 50y or older

Exclusion criteria

  • Taking medications that might affect bone
  • Conditions that might preclude participating in a resistance-training program (determined by the "Get Active Questionnaire").
  • Planning 6 weeks of travel during the 12 month intervention period
  • Planning major surgery during the 12 month intervention period
  • Already strength training greater than 2 days per week for 30 minutes or longer per session
  • Allergies to ingredients in the beverages

Treatment and study plan

Nutritional supplementation during a 12 month resistance training program

Dietary Supplement

1% chocolate milk

Primary outcomes

  1. Change in section modulus at the hip (cm to the power of 3)

    Time frame: 12 months

    Section modulus measured by dual energy X-ray absorptiometry

Secondary outcomes

  1. Change in lumbar spine bone mineral density (g/cm-squared)

    Time frame: 12 months

    Lumbar spine bone mineral density measured by dual energy X-ray absorptiometry

  2. Change in hip bone mineral density (g/cm-squared)

    Time frame: 12 months

    Hip bone mineral density measured by dual energy X-ray absorptiometry

  3. Change in cross-sectional area at the hip (cm-squared)

    Time frame: 12 months

    Cross-sectional area measured by dual energy X-ray absorptiometry

  4. Change in cortical thickness at the hip (cm)

    Time frame: 12 months

    Cortical thickness measured by dual energy X-ray absorptiometry

  5. Change in buckling ratio at the hip (no units)

    Time frame: 12 months

    Buckling ratio measured by dual energy X-ray absorptiometry

  6. Change in bench press strength (kg)

    Time frame: 6 and 12 months

    Bench press strength determine from 1-repetition maximum

  7. Change in knee extension strength (kg)

    Time frame: 6 and 12 months

    Knee extension strength determined from 1-repetition maxium

  8. Change in lean tissue mass (kg)

    Time frame: 12 months

    Lean tissue mass measured by dual energy X-ray absorptiometry

  9. Change in fat mass (kg)

    Time frame: 12 months

    Fat mass measured by dual energy X-ray absorptiometry

  10. change in 30 second sit to stand (number of repetitions)

    Time frame: 6 and 12 months

    Maximal number of times sitting and standing in 30 seconds

  11. Change in walking speed (m/s)

    Time frame: 6 and 12 months

    walking speed measured over 10 m

  12. Change in timed up and go performance (s)

    Time frame: 6 and 12 months

    Time for standing from a chair, walking 6 meters and sitting back down

Study contacts

Contact information is provided by the study sponsor or research team.

Philip Chilibeck, PhD

CONTACT

[email protected]

3062303849

Sponsors and collaborators

Lead sponsor

University of Saskatchewan

Other

Registry information

Official study title

Dairy Versus Plant-based Beverages Combined With Resistance-training for Improving Bone Health

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Apr 27, 2025
Registry last updated
Feb 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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