DAILIES TOTAL1® - Comparative Assessment of Tear Film Evaporation

This study consists of 5 visits (1 screening, 4 assessment) with a maximum of 6 days between assessment visits and at least 24 hours of no lens wear the day prior to the visit. Each subject will be randomized to a crossover sequence of 4 periods. Different study lenses will be worn during 3 of the periods, for at least 8 hours each, and the remaining period will have no lens wear.

Inclusion criteria

• Sign an informed consent document;
• Adapted, current soft contact lens wearer;
• Symptoms of contact lens discomfort as defined by the Symptomatology (Eligibility) Questionnaire;
• Can be successfully fitted with study lenses;
• Willing to wear lenses for a minimum of 8 hours prior to each study visit;
• Willing to discontinue artificial tears and rewetting drops usage on the days of study visits;
• Other protocol-specified inclusion criteria may apply.

Exclusion criteria

• Ocular anterior segment infection, inflammation, abnormality, or active disease that would contraindicate contact lens wear;
• Use of systemic or ocular medications for which contact lens wear could be contraindicated as determined by the investigator;
• Monocular (only 1 eye with functional vision) or fit with only one lens;
• History of herpetic keratitis, ocular surgery, or irregular cornea;
• Known pregnancy and lactation;
• Other protocol-specified exclusion criteria may apply.