Skip to main content
OpenTrials
Completed

NCT Number: NCT03790254

D Mannose for Prevention and Treatment of RUTIs

The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Recurrent Urinary Tract Infections Antibiotic Prophylaxis Antibiotic Resistance Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Infections Male Urogenital Diseases Urinary Tract Infections Urogenital Diseases Urologic Diseases

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Urology Department Fondazione IRCCS Policlinico San Matteo

Pavia, 27100, Italy

About this study

A comprehensive systematic MEDLINE, Embase, Cochrane search was performed for English language reports published before December 2018 using the term "recurrent urinary tract infections and d mannose." We searched Medline, Embase, and the Cochrane Register of Controlled Trials since January 2010 to December 2018. Eligible studies did not include non-oral therapy, local (vaginal) treatment in women with RUTIs.

Study eligibility criteria- We identified eligible original articles. The heterogeneity of the available studies, their different rationale and aim, the assumption of d mannose for prophylaxis or treatment of recurrent UTIs need to be taken into account.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

recurrent urinary tract infections (RUTIs)

Exclusion criteria

Upper urinary tract infections, severe clinical symptoms, fever > 37,5 with lumbar pain

Treatment and study plan

Systematic review

Other

Primary outcomes

  1. research literature data on d mannose for prevention and treatment of recurrent urinary tract infections.

    Time frame: January 2010-December 2018

    literature search of the Medline, Embase, and Cochrane Library databases

Sponsors and collaborators

Lead sponsor

Fondazione IRCCS Policlinico San Matteo di Pavia

Other

Registry information

Official study title

Oral D Mannose in the Prevention and Treatment of Recurrent Urinary Tract Infections: a Systematic Review

Acronym: mannoseRUTIs

Important dates

Study start
2010
Primary completion
2018
Study completion
2018
First posted
Dec 31, 2018
Registry last updated
Dec 31, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.