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Completed

NCT Number: NCT01111474

Cyanoacrylate and Laser and Dentin Sensitivity

This study aimed to evaluate the effectiveness of two treatments for dental hypersensitivity: cyanoacrylate (Super Bonder®) compared with use of low intensity laser treatment (LILT). As the cyanoacrylate is a lower cost treatment, the hypothesis in investigation is if this product is equally effective as the laser treatment.

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Key information

Conditions

Dentin Hypersensitivity Dentin Sensitivity Stomatognathic Diseases Tooth Diseases

Age range

12 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

The present study included 62 patients (15 male and 47 females, aged 12 to 60 years). The initial cervical dentin hypersensitivity was checked throughout a thermal test (air blast). The 434 teeth included were that with a score ≥5 in a numerical scale rating of pain. Teeth were randomly assigned according quadrants (split mouth design) - 216 were allocated to LILT group and 218 for the Super Bonder® group. Thermal tests with a tetrafluoroethane spray (Endo-Ice®) and air blast were performed and considered as baseline. Pain parameters were recorded using a numerical scale rating with 24 hours, 30, 90 and 180 days after the interventions. Quality of life of the patients was also assessed with the use of OHIP-14 at baseline and after 180 days.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients should be in good general and dental health;
  • present complaints of dental sensitivity to cold, sweet, acidic foods and brushing;
  • present complaints of pain in teeth located in different quadrants;
  • manifest pain or discomfort upon application of the triple syringe air jet;
  • not be in current use of desensitizing agents.

Exclusion criteria

  • presence of extensive restorations and carious lesions in the sensitive teeth;
  • undergoing orthodontic treatment;
  • frequent use of analgesics, antidepressants and anti-inflammatory drugs;
  • presence of gingival inflammation;
  • non-consent of patient.

Treatment and study plan

Cyanoacrylate

Other

3 applications of cyanoacrylate (48 hours interval) at the cervical region of the sensitive tooth

Other names: Superbonder

Laser

Radiation

This process was conducted three times with an interval of 48 hours between applications, according to laser's manufacturer advice Clean Line Easy Laser - LILT®, Clean Line Easy Laser Doctor Dental Products Industry LTDA, BRA). For dentin hypersensitivity, the application of 1Joule/cm^2 is recommended for eight seconds at three points along the dental neck, using the infrared wavelength (795nm).

Other names: LILT

Primary outcomes

  1. Change of the Pain Sensitivity

    Time frame: Baseline and 180 days

    Change in pain experienced by the participants was calculated as the difference between baseline level of pain sensitivity and after 180 days. Pain was recorded using a numerical pain assessment scale with range between 0 (no pain) to 10 (worst possible pain). The higher the numbering the worse the result.

Secondary outcomes

  1. Quality of Life Improvement

    Time frame: Baseline and 180 days

    Difference between the level of quality of life - Oral Health Impact Profile "OHIP" at baseline and 180 days. OHIP-14 total scale ranges from 0 to 56 points with higher scores indicating a poorer oral health-related quality of life. The response format uses a Likert-type frequency scale such as follows: very often = 4, fairly often = 3, occasionally = 2, hardly ever = 1, never = 0. Total score is obtained by summing the response codes of the 14 items constituting the measure.

Sponsors and collaborators

Lead sponsor

Federal University of São Paulo

Other

Collaborators

  • Federal University of the Valleys of Jequitinhonha and Mucuri

Registry information

Official study title

Effectiveness of Cyanoacrylate and Laser in the Treatment of Cervical Dentin Sensitivity

Acronym: Cyano-laser

Important dates

Study start
2008
Primary completion
2008
Study completion
2009
First posted
Apr 27, 2010
Registry last updated
Aug 17, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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