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Completed

NCT Number: NCT05674955

CWT Versus AT on Selected Cardiovascular Indices and Functional Capacity in Patients With Ischemic Cardiomyopathy.

To compare between the effect of circuit weight and aerobic training on selected cardiovascular indices and functional capacity in patients with ischemic cardiomyopathy.

Completed

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Key information

Age range

45 year–55 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Cairo University

Giza, Egypt

About this study

Ischemic cardiomyopathy (ICM) is a term that refers to the heart's decreased ability to pump blood properly due to myocardial damage brought upon by ischemia. Ischemic cardiomyopathy has a spectrum of clinical changes which eventually leads to congestive heart failure (CHF). Initially, there is a reversible loss of cardiac contractile function because of decreased oxygen supply to the heart muscle; however, when there is ischemia for a prolonged period, there is irreversible cardiac muscle damage resulting in cardiac remodeling. Remodeling is primarily achieved by myocardial fibrosis which results in decreased cardiac function, arrhythmia, and possible cardiac conduction system impairment. In ischemic cardiomyopathy, there is a significant impairment of the left ventricular systolic function, with a left ventricular ejection fraction (LVEF) less than 40% (Bhandari et al., 2021).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Sixty male patients with ischemic cardiomyopathy as a result of a recent acute myocardial infarction event (≤2 months) with 40%<LVEF<50%.
  • They are functionally classified as class II according to New York Heart Association (NYHA).
  • Their age will be ranged from 45 to 55 years old.
  • Their BMI will be ranged from 25 to 29.9 kg/m².
  • They will have good mentality.

Exclusion criteria

  • Recurrent coronary heart disease.
  • Severe valvular diseases.
  • Underlying pulmonary disease (aspiration pneumonia, chronic obstructive pulmonary disease, pneumothorax, etc.).
  • Inability to ambulate owing to physical problems (paresis induced by cerebral stroke, spinal cord injury, amputation, severe pain, dyspnea, etc.).
  • muskloskletal problems (e.g. severe osteoarthritis or ankylosing spondylitis).
  • Impaired cognitive function (vascular dementia, Alzheimer's dementia, other psychological disease, etc.)

Treatment and study plan

Circuit weight versus aerobic training

Diagnostic Test

Circuit weight :Duration: 30 min-60 min (total session) Frequency: 3 times / week. Intensity: increased load was established when subject was able to complete 12 repetitions ( Wayne, 2014)

B- Aerobic training:

This mode of exercise will be conducted for study group B as follows:

Intensity: started by 60-85% of target heart rate according to each patient response Target heart rate (THR) = 60% -85% (maximum heart rate-resting heart rate) + resting heart rate Maximum heart rate (MHR) = (220-Age). Mode: Walking on treadmill. Duration: Each session consisted of 10 minutes warming up firstly then 30 minutes time of session ended by 10 minutes cool down exercises.

Frequency: Three times / week (Nishi et al., 2011).

C-Traditional medical treatment:

This treatment will be conducted for all group A, B and C.

Primary outcomes

  1. Ejection fraction

    Time frame: 2 months

    Will be measured by precentge

Secondary outcomes

  1. Blood pressure

    Time frame: 2 months

    Will be measured by mmhg

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Circuit Weight Versus Aerobic Training on Selected Cardiovascular Indices and Functional Capacity in Patients With Ischemic Cardiomyopathy.

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jan 9, 2023
Registry last updated
Jul 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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