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Recruiting

NCT Number: NCT04157569

CtDNA After Chemotherapy in Elderly Patients With Acute Leukemia

This study will monitor CtDNA After Chemotherapy in Elderly Patients With AL

Recruiting

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Key information

Conditions

Acute Leukemia

Age range

60 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

This study will use droplet digital PCR (ddPCR) method to quantify peripheral blood plasma mutant allele frequency (MAF) in elderly acute leukemia patients after chemotherapy to evaluate the clinical value of CtDNA .

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Written informed consent
  • Male
  • not pregnant female
  • patients >=60 years old
  • Diagnosis of acute leukemia

Exclusion criteria

  • Pregnancy
  • HIV positive
  • patients >=100 years old

Treatment and study plan

Primary outcomes

  1. cumulative incidence of relapse(CIR)

    Time frame: through study completion, an average of 1 year

    cumulative incidence of relapse

Secondary outcomes

  1. overall survival (OS)

    Time frame: through study completion, an average of 2 years

    overall survival

Study contacts

Contact information is provided by the study sponsor or research team.

Liren Qian, MD

CONTACT

[email protected]

+861066957676

Sponsors and collaborators

Lead sponsor

Navy General Hospital, Beijing

Other

Registry information

Official study title

Monitoring Circulating Tumor DNA After Chemotherapy in Elderly Patients With Acute Leukemia

Important dates

Study start
2019
Primary completion
2024
Study completion
2029
First posted
Nov 8, 2019
Registry last updated
Feb 25, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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