CT Scan Sizing for Perceval Sutureless Valve

Recent evidence in TAVI patients suggests that significant underexpansion or distortion of valved stents may be associated with altered leaflet function, leading to increased transprosthetic gradients and possibly predisposing to other negative outcomes such as valve thrombosis, low platelet counts, thromboembolic events, and early degeneration . Moreover, there is evidence that excessive oversizing of the Perceval valve is detrimental.

The present study is aimed to investigate the relationship between the CT-derived measure of the annulus dimension and early hemodynamic and clinical outcomes in patients undergoing sutureless aortic valve replacement (AVR) with the Perceval sutureless aortic valve and define the Perceval sizing chart based on preoperative CT-scan measurements.

Inclusion criteria

• Male and female subjects > 18 years;
• Subjects willing to sign and date an informed consent for treatment of personal data;
• Subjects willing and able to comply with the follow up schedule of the protocol;
• Subjects with indication for aortic valve replacement on a tricuspid aortic valve;
• Subjects with possibly associated need for coronary revascularization.
• Subjects with Ejection Fraction ≥ 40%

Exclusion criteria

• Male and female subjects ≤ 18 years;
• Subjects with bicuspid aortic valve
• Subjects with associated mitral valvulopathy or ascending aorta aneurysm
• Subjects with pure aortic insufficiency
• Subjects with Ejection Fraction < 40%
• Subjects with acute myocardial infarction < 30 gg
• Subjects with serum creatinine > 2 mg/Dl