Cryotherapy and Body Slimming

Prospective, monocentric pilot and comparative (before and after) study in simple blind (assessor different from the operator).

• The effectiveness of cryotherapy will be evaluated by the metric measurement of the treated areas: waist circumference, from the hips to the level of the saddlebags.
• Measurement of subcutaneous fat mass with iDXA scanner on treated areas
• Metabolic parameters from a blood test: Liver function (AST, ALT, gamma GT), inflammatory markers, plasmatic fatty acids, glycerol, total cholesterol, triglycerides, lipids, blood sugar, insulin, lactate.

Inclusion criteria

• Patients ≥ 18 years old and non-menopausal with a BMI between 20 and 30 (20≥IMC≤30), with an overload of abdominal subcutaneous fat tissue and at the saddlebags

Exclusion criteria

• - < 18 years old.
• Pregnancy
• Breastfeeding
• Cold allergy: 2-minute ice cube test positive
• A waist/hip ratio indicative of a pathological fat distribution (>0.8 for women, >0.9 for men)
• Endocrine pathologies (Cushing's disease, endocrine tumours, unbalanced frank or labile hypothyroidism, hirsutism and hyper-androgenism, insulin resistance and/or unbalanced type 2 diabetes...)
• Neoplasia
• Psychiatric pathologies with or without treatment (Antidepressants, Neuroleptics, Anxiolytics...), well characterized anorexia-bulimia syndromes.
• Established alcoholism. Daily alcohol consumption should not exceed 2 glasses of wine per day.
• Digestive pathologies (especially hepatic) and functional digestive disorders (chronic constipation, alternating constipation-diarrhoea, chronic abdominal pain).
• Weaknesses of the abdominal wall (umbilical, inguinal, crural hernias)
• HIV in therapy
• Genetic deformities and diseases
• Vegetarian/vegetarian diet, macrobiotic diet
• Spasmophilia
• Surgery less than 3 months old
• Unbalanced coronary artery disease, untreated angina