Charité-Universitätsmedizin Berlin
Berlin, 13353, Germany
Completed
NCT Number: NCT02963298
CRRT for Glutamate Elimination After Cardiac Arrest
Glutamate is known to be a mediator for apoptosis after brain hypoxia e.g. due to cardiac arrest. This pilot trial evaluates the possibility of elimination of Glutamate by CRRT after cardiac arrest.
Completed
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Notify MeKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- post cardiac arrest
Exclusion criteria
- hemodynamic instable
- in-hospital cardiac arrest
Treatment and study plan
Continuous Renal Replacement Therapy
ProcedurePrimary outcomes
-
Glutamate blood concentration in intervention arm over the time
Time frame: 72 hours
Reduction of blood Glutamate concentration by renal replacement therapy
Secondary outcomes
-
number of participants with abnormal outcome parameters
Time frame: up to 14 days
Sponsors and collaborators
Lead sponsor
C. Storm
Other
Registry information
Official study title
Pilot Trial Concerning Glutamate Elimination With CRRT for Neurological Outcome After Cardiac Arrest
Acronym: GCRRT
Important dates
- Study start
- 2016
- Primary completion
- 2017
- Study completion
- 2017
- First posted
- Nov 15, 2016
- Registry last updated
- Jun 21, 2019
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.