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NCT Number: NCT03465150

Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital

With 24 million results associated with Google's searchon keywords "severe acne", Pr Dreno's team understand better thatthis disease, which affects many French people, is a real concern of Public Health and not a "forced evil" of the adolescent period, which will eventually resolve itself. Acne does not affect the vital prognosis, but its psychosocial impact is major and should not be underestimated. Paradoxically, despite the high prevalence of acne, few quality epidemiological studies have been published. Physicians are often helpless when faced with patients' questions. They often need a lot of explanations, especially on the factors aggravating this dermatosis, which greatly affects their quality of life.

This cohort, the first of its kind in France, will determine the predictive factors of therapeutic response, endogenous and environmental factors impacting on the severity of acne assess the quality of life and psychological impact of acne patients, determine the patient's course of care and the associated costs. Pr Dreno's team will also build up a bio collection (bacteriological samples).

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Key information

Conditions

Acne Acne Vulgaris Acneiform Eruptions Sebaceous Gland Diseases Skin Diseases Skin and Connective Tissue Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU de Nantes

Nantes, 44000, France

Location status: Recruiting

Location contact

Brigitte Dreno, PU-PH

CONTACT

[email protected]

About this study

All patients going for the first time in specialized consultation "acne" at Nantes University Hospital , and who meet the inclusion criteria will be included in the COPACNE cohort. Inclusion will take place at the first consultation, after information and agreement of the patient and, if applicable, his or her legal representatives. The frequency of each patient's follow-up visits will be determined on a case-by-case basis according to the patient's medical needs (generally, the interval between 2 visits is between 1 and 4 months).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient with acne
  • Patient (or parents/guardians for minors) who are not opposed to participating in the cohort.
  • Subjects affiliated to an appropriate health insurance

Exclusion criteria

  • Dermatosis of the face other than acne
  • Refusal to participate by the minor or parent/guardian
  • Adults under a legal protection regime (guardianship, trusteeship, judicial safeguard)

Treatment and study plan

acne

Other

Patient with acne

Other names: acne vulgaris

Primary outcomes

  1. Measure of Acne stage

    Time frame: 2 years

    composite criteria. the scale is GEA for Global Evaluation Acne Scale with 0 no acne to 5 severe acne

Secondary outcomes

  1. assessing patients' quality of life

    Time frame: 2 years

    composite criteria. CADI score is calculated by summing the score of each question resulting in a possible maximum of 15 and a minimum of 0. The higher the score, the more the quality of life is impaired.

  2. cost of acne illness

    Time frame: 2 years

    reimbursement data relating to hospitalizations and care in town recorded by the Health Insurance in the SNIIRAM database.

  3. Bacteriological sample to find Propionibacterium acnes, Hormonal check-up on blood sample

    Time frame: 2 years

    Correlation between bacterial and blood samples and the efficacity of the treatment

Study contacts

Contact information is provided by the study sponsor or research team.

Amir khammari

CONTACT

[email protected]

Brigitte DRENO

CONTACT

[email protected]

0240083137

Sponsors and collaborators

Lead sponsor

Nantes University Hospital

Other

Registry information

Official study title

Creation of a Monocentric Cohort of Patients Treated for Acne at the Nantes University Hospital: the COPACNE Cohort.

Acronym: COPACNE

Important dates

Study start
2018
Primary completion
2033
Study completion
2033
First posted
Mar 14, 2018
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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