CHRU Amiens
Amiens, 80480, France
NCT Number: NCT07072975
Exercise retraining improves the prognosis and quality of life of patients with chronic lung or circulatory diseases. However, exercise intolerance may be caused by excessive ventilatory. Exposure to oxygen-replete air reduces this ventilatory overload, improves sleep and enhances responses to exercise. This study examine the impact of the acute manipulation of oxygen availability during inter-exercise recovery period of an intermittent cycling exercise on perceptual responses.
this randomized, controlled, study include adult patient with COPD. On separate days, 50 patients with COPD completed four sets of 4-min at 85% of VO2peak intercept by 3-min of passive recovery in two randomized between-sets recovery conditions. Rating exertion perception, gaz exchanges, heart rate, sleep quality and nocturnal heart rate variability were assessed.
Hypoxic exposure during inter-repetition recovery phases would reduce the ventilatory load during exercise. What's more, patients would not be forced to perform the sporting gesture in a restricted space or wearing a mask, limiting dyspnea and the perceived difficulty of the effort. Lastly, the induction of hypoxic stress during the re-training session helped to improve patients' sleep.
Trial opening soon.
Get Notified40 year–60 year
All sexes
Interventional
Not applicable
Amiens, 80480, France
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
-
Normobaric hypoxia (inspired oxygen fraction of 12.9%) applied between-sets recovery periods
Between-sets recovery periods under normoxic condition
Time frame: day 1
The modified Borg CR10 RPE scale measures exertion on a scale of 0 (no exertion or resting) to 10 (pushing yourself to the max).
Time frame: day 1
Cardiorespiratory responses to exercise is measured with gaseous exchange volumes
Contact information is provided by the study sponsor or research team.
Centre Hospitalier Universitaire, Amiens
Other
Acronym: HypoChronoPerf
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