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Active, Not Recruiting

NCT Number: NCT04331509

COVID-19 Symptom Tracker

The viral Covid-19 outbreak is now considered a pandemic according to the World Health Organisation (WHO). A free monitoring app 'COVID-19 Symptom Tracker' has been developed to record and monitor the symptoms of the COVID-19 coronavirus infection; tracking in real time how the disease progresses. The app also records how measures aimed at controlling the pandemic including self-isolation and distancing are affecting the mental health and well-being of participants. The data from the study will reveal important information about the symptoms and progress of COVID-19 infection in different people, and why some go on to develop more severe or fatal disease while others have only mild symptoms do not.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

King's College London, London, United Kingdom

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About this study

A free monitoring app 'COVID-19 Symptom Tracker' has been developed by health technology company Zoe Global Limited in collaboration with scientists at King's College London, Harvard Medical School, Massachusetts General Hospital and Stanford University. A web-based equivalent is being developed for those unable to download this app. This new app records and monitors the symptoms of COVID-19 coronavirus infection; tracking in real time how the disease progresses. The app also records how measures aimed at controlling the pandemic including self-isolation and distancing affect the mental health and well-being of participants. The app also allows self-reporting where no symptoms are experienced such that it records any users that feel healthy and normal.

The app, has been launched in both the UK and the US. Researchers in other countries are encouraged to obtain the required approvals from Apple and Google to make the app available in their territories.

The data from the study will reveal important information about the symptoms and progress of COVID-19 infection in different people, and why some go on to develop more severe or fatal disease while others have only mild symptoms do not.

It is also hoped that the data generated from this study will help the urgent clinical need to distinguish mild coronavirus symptoms from seasonal coughs and colds, which may be leading people to unnecessarily self-isolate when they aren't infected or inadvertently go out and spread the disease when they are.

Users download the free app COVID-19 Symptom Tracker and record information about their health on a daily basis, including temperature, tiredness and symptoms such as coughing, breathing problems or headaches.

The app is available internationally to the general population and will also be used in two large epidemiological cohorts: The TwinsUK cohort (n=15,000) and Nurses Health Study (n=280,000).

The app will allow scientists to study the spread and development of symptoms across whole populations, both in the UK and abroad, as well as detailed genetic and other studies, particularly with the twins cohort

Any data gathered from the app and study will be used strictly for public health or academic research and will not be used commercially or sold.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults of 18 years and above, both in the UK and internationally where the app has been approved for download from the Apple App store and Google Play. The web-based equivalent to the app will also be made available via a link for those unable to download.

Exclusion criteria

  • Anyone below the age of 18; anyone unable to provide informed consent.

Treatment and study plan

No intervention

Other

No Intervention

Primary outcomes

  1. Physical health symptoms

    Time frame: 1 day

    Self reported as physically healthy (tick box)

  2. Lack of physical health symptoms

    Time frame: 1 day

    Self reported as physically not feeling healthy (tick box)

Secondary outcomes

  1. Fever

    Time frame: 1 day

    Self reported remperature (Degrees Celsius)

Other outcomes

  1. Cough

    Time frame: 1 day

    Self reported cough (drop down menu; yes/no)

  2. Fatigue

    Time frame: 1 day

    Self reported fatigue (drop down menu; yes/no)

  3. Headache

    Time frame: 1 day

    Self reported headache (drop down menu; yes/no)

  4. Shortness of breath

    Time frame: 1 day

    Self reported shortness of breath (drop down menu; yes/no)

  5. Sore throat

    Time frame: 1 day

    Self reported sore throat (drop down menu; yes/no)

  6. Loss of smell/ taste

    Time frame: 1 day

    Self reported loss of smell/ taste (drop down menu; yes/no)

  7. Hoarse voice

    Time frame: 1 day

    Self reported hoarse voice (drop down menu; yes/no)

  8. Chest pain or tightness

    Time frame: 1 day

    Self reported chest pain or tightness (drop down menu; yes/no)

  9. Abdominal pain

    Time frame: 1 day

    Self reported abdominal pain (drop down menu; yes/no)

  10. Diarrhoea

    Time frame: 1 day

    Self reported diarrhoea (drop down menu; yes/no)

  11. Confusion

    Time frame: 1 day

    Self reported confusion (drop down menu; yes/no)

  12. Skipping meals

    Time frame: 1 day

    Self reported skipping meals (drop down menu; yes/no)

Sponsors and collaborators

Lead sponsor

King's College London

Other

Collaborators

  • Harvard School of Public Health (HSPH)
  • Massachusetts General Hospital
  • Stanford University
  • Zoe Global Limited

Registry information

Important dates

Study start
2020
Primary completion
2026
Study completion
2026
First posted
Apr 2, 2020
Registry last updated
Mar 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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