Skip to main content
OpenTrials
Completed

NCT Number: NCT04503447

COVID-19 Seroprevalence Study in ITM Staff

In Belgium, the corona virus disease 2019 (COVID-19) epidemic is in the growing phase of its second wave.

The Belgian crisis cell is balancing between allowing the economy to recover and minimize the disease spread. To decide which containment measures should be maintained, reinstalled or suspended, information on what proportion of people has been infected and on possible risk factors for virus transmission can be helpful.

This study will be conducted on staff members of the ITM. All staff members will be invited to participate. Participants will be asked to have a blood sample drawn for detections of antibodies against SARS-CoV-2 (using one of these two commercial assays: Anti-SARS-CoV-2 ELISA (EUROIMMUN) or WANTAI SARS-CoV-2 Ab ELISA (WANTAI SARS-CoV-2 Diagnostics)) and to complete a questionnaire about their exposure, both within and outside the ITM, to the SARS-CoV-2, and about their health and symptoms. The primary objective is to estimate the occurrence rate of anti-SARS-CoV-2 antibodies or seroprevalence in ITM staff. Secondary objective is to estimate the SARS-CoV-2 seroprevalence in ITM staff member groups, stratified by variables obtained through the questionnaire, such as age, gender, symptoms, exposure to COVID-19 patients/samples, comorbidities, adherence to containment measures.

Completed

Looking for future studies?

Notify Me

Key information

About this study

The study is observational and will be conducted on ITM staff members. All members will be invited to participate.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be an active ITM staff member
  • Be willing and able to complete the questionnaire
  • Be willing and able to provide informed consent

Exclusion criteria

  • Doctor of Philosophy (PhD) students, Master students and interns of the ITM

Treatment and study plan

Primary outcomes

  1. SARS-CoV-2 seroprevalence ITM staff

    Time frame: Sample is drawn once, within 7 days after recruitment

    The proportion of participating ITM staff members with detectable SARS-CoV-2 antibodies

Secondary outcomes

  1. SARS-CoV-2 seroprevalence in ITM staff, stratified by variables

    Time frame: Questionnaire is completed once, at recruitment

    SARS-CoV-2 seroprevalence in ITM staff members stratified by variables obtained through the questionnaire, such as age, gender, symptoms, exposure to COVID-19 patients/samples, comorbidities, adherence to containment measures.

Other outcomes

  1. Risk or protective factors for SARS-CoV-2 seropositivity

    Time frame: Questionnaire is completed once, at recruitment

    To identify factors that are associated with an elevated or reduced risk of seropositivity in ITM staff and the Belgian working population in general.

Sponsors and collaborators

Lead sponsor

Institute of Tropical Medicine, Belgium

Other

Registry information

Official study title

Severe Acute Respiratory Syndrome Coronavirus (CoV) 2 (SARS-CoV-2) Seroprevalence Study in Institute of Tropical Medicine (ITM) Staff

Acronym: CovAb

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Aug 7, 2020
Registry last updated
Oct 22, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.