COVID-19 - SARS-CoV-2 Community Contamination in Children and Adults - Impact of Variants (Dyn3CEA - Nosocor Phase 2)

Unlike other respiratory viruses such as influenza and RSV where the child is the essential reservoir and central vector of intrafamilial contamination, the child is likely to be a small player in the transmission of CoV2-CoRSA infection. This study aims to describe the age category of the first contact, within 14 days before the appearance of the first symptoms of the index case in order to describe the age categories of this first contaminant, globally, in the group of children and finally in the group of adults. This work is intended to provide food for discussion and to justify the distancing and containment measures imposed on children when their isolation has a deleterious impact that has now been established for some children.

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Key information

Conditions

Infection Viral Infections Virus Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

Hôpital Femme Mère et enfant

Lyon, Auvergne-Rhône-Alpes, 69003, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

1) Children hospitalized in the Pediatric department of the Hospices Civils de Lyon with PCR positive for a variant of the historical SARS-CoV2, 2) Adults hospitalized in the the Hospices Civils de Lyon, for a Covid-19 disease with documented infection by a variant of the SARS-CoV-2 and included in the NOSO-COR study with matching criteria described below.

Exclusion criteria

Any patient suspected of nosocomial infection.
Any patient death during the Covid-19 infection.
Any adult patient without children living home.
Opposition to participate.

Treatment and study plan

Review of medical file

Other

Review of medical patient file, including patient tracing, brief summary of the disease course, barrier gestures, social distancing.

Phone call interview

Other

less than 15 minutes phone call

Primary outcomes

Percentage of possible contaminants, adults, adolescents and children with Covid-19

Time frame: At inclusion

To describe the age category of the 1st possible contaminant in the index case to show the preponderance of possible adult and adolescent contaminants in the SARS-Cov-2 contamination.

Primary endpoint: Percentage of possible contaminants, adults, adolescents and children, in matched children and adults with Covid-19.

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Official study title

Epidemiology of CoV-2 SARS Infections: Dynamics of Community Contamination in Children and Adults - Impact of Variants

Important dates

Study start: 2021
Primary completion: 2021
Study completion: 2021
First posted: Jun 14, 2021
Registry last updated: Jan 4, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed