COVID-19 - SARS-CoV-2 Community Contamination in Children and Adults (Dyn3CEA_Nosocor)

Unlike other respiratory viruses such as influenza and Respiratory Syncytial Virus (RSV) where the child is the essential reservoir and central vector of intrafamilial contamination, the child is likely to be a small player in the transmission of Severe Acute Respiratory Syndrome CoronaVirus 2 (SRAS-CoV2) infection. This study aims to describe the age category of the first contact, within 14 days before the appearance of the first symptoms of the index case in order to describe the age categories of this first contaminant, globally, in the group of children and finally in the group of adults. This work is intended to provide food for discussion and to justify the distancing and containment measures imposed on children when their isolation has a deleterious impact that has now been established for some children.

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Key information

Conditions

Infection Viral Infections Virus Diseases

Age range

0 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Service de Reanimation Pediatrique

Lyon, Rhone, 69003, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Children after hospitalized in Hospices Civils de Lyon with Polymerase Chain Reaction (PCR) positive SARS-CoV2,
Adults hospitalized in Hospices Civils de Lyon and included in the NOSO-COR study with matching criteria described below.

Matching will be performed on family age characteristics and on the period of contamination included in the containment period to minimize bias, and if possible frequency matching according to admission in Intensive Care Unit ICU/Pediatric Intensive Care Unit (PICU), and to family structure (n of children / n of adults in the family).

Exclusion criteria

Any patient suspected of nosocomial infection.
Any patient death during the Covid-19 infection.
Any adult patient without children living home.
Opposition to participate.

Treatment and study plan

review of medical patient file

Other

Review of medical patient file, including patient tracing, brief summary of the disease course, barrier gestures, social distancing.

Phone call interview

Other

less than 15 minutes phone call

Primary outcomes

Percentage of possible contaminants, adults, adolescents and children with Covid-19

Time frame: at inclusion

To describe the age category of the 1st possible contaminant in the index case to show the preponderance of possible adult and adolescent contaminants in the SARS-Cov-2 contamination.

Percentage of possible contaminants, adults, adolescents and children, in matched children and adults with Covid-19.

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Official study title

Epidemiology of CoV-2 SARS Infections: Dynamics of Community Contamination in Children and Adults

Important dates

Study start: 2020
Primary completion: 2021
Study completion: 2021
First posted: Dec 11, 2020
Registry last updated: Apr 26, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed