COVID-19 and Acute Invasive Fungal Rhinosinusitis

Data for acute invasive rhinosinusitis was obtained from the Otorhinolaryngology departments at our tertiary hospital at the period from January 2017 to December 2020. Then the risk factors of comorbid diseases and fungal types between post-Covid-19 and non-Covid-19 groups regarding the incidence of invasive rhinosinusitis are compared.

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Key information

Conditions

Covid19 COVID-19 Coronaviridae Infections Coronavirus Infections Infections Lung Diseases Nidovirales Infections Nose Diseases Otorhinolaryngologic Diseases Paranasal Sinus Diseases Pneumonia Pneumonia, Viral RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Rhinitis Rhinosinusitis Sinusitis Virus Diseases

Age range

15 year–90 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients of any age and sex. invasive rhinosinusoitis diagnosis based on clinical , endoscopic diagnosis
Positive findings for acute sinusitis on sinus computed tomography (CT) scan in addition to fungal determination by histopathological examination of specimen of affected tissues for detection of the type of fungi.
Positive PCR was confirmed from the patient's files at the isolation hospitals for COVID 19 group.

Exclusion criteria

Patients who completed management outside our hospital

Treatment and study plan

Fungal rhinosinusitis

Diagnostic Test

Pathology examination

Primary outcomes

Fungus detection

Time frame: 2 weeks

Culture and microscopic examination by the light microscope to examine the different types of the fungi using hematoxylin & eosin stain and Periodic acid-Schiff stain which is positive in fungi

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

The Impact of COVID-19 Outbreak on The Incidence of Acute Invasive Fungal Rhinosinusitis

Important dates

Study start: 2017
Primary completion: 2020
Study completion: 2020
First posted: Mar 22, 2021
Registry last updated: Mar 22, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed