Costs of Opportunistic Upper Gastrointestinal Endoscopy and the Economic Burden of Gastric Cancer Management

Data will be extracted from routinely collected hospital databases.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Gastric Cancer (GC) Digestive System Diseases Digestive System Neoplasms Gastric Adenocarcinoma Gastrointestinal Diseases Gastrointestinal Neoplasms Neoplasms Neoplasms by Site Stomach Diseases Stomach Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Unidade Local de Saúde do Alto Alentejo

Portalegre, 7300-060, Portugal

About this study

Electronic medical records; Endoscopy and pathology databases; Surgical and hospitalization records; Oncology treatment databases; Imaging and diagnostic services; Institutional mortality records.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Cohort A:

Eligible participants were adults aged 50 to 75 years or older who had been referred for colonoscopy as part of the national colorectal cancer screening programme, following a positive FIT. To be included, individuals also needed to provide informed consent and agree to undergo an EGD endoscopy for the screening of potential upper gastrointestinal precancerous conditions or lesions.

Cohort B:

Patients with gastric adenocarcinoma, diagnosed and treated at Unidade Local de Saúde do Alto Alentejo between 2015 and 2025.

Exclusion criteria

Cohort A:

Exclusion criteria included a prior diagnosis of gastric cancer, as well as any condition that would prevent the safe performance of the EGD or the collection of gastric mucosal biopsies. Previous EGD was not listed as an exclusion criterion.

Cohort B:

Other types of gastric tumors.
Gastric involvement from metastatic disease of another primary tumor.

Treatment and study plan

Primary outcomes

Stage distribution at diagnosis

Time frame: At diagnosis (2015-2020)

Distribution of gastric cancer stages at diagnosis (Stage I-IV) according to TNM classification (expressed as percentage of patients per stage).
Treatment patterns

Time frame: During initial treatment period (2015-2020)

Types of treatment received by patients with gastric cancer, including surgery, chemotherapy, radiotherapy, and palliative care
Overall survival

Time frame: From diagnosis up to last follow-up (2015-2020)

Overall survival of patients diagnosed with gastric cancer (measured in months).

Sponsors and collaborators

Lead sponsor

Unidade Local De Saúde Do Norte Alentejano

Other

Registry information

Official study title

Real-world Incremental Costs of Opportunistic Upper Gastrointestinal Endoscopy Added to Colorectal Cancer Screening and the Economic Burden of Gastric Cancer Management: a Retrospective Cohort Study - Study Protocol

Acronym: EconROGCAS

Important dates

Study start: 2026
Primary completion: 2026
Study completion: 2026
First posted: Apr 13, 2026
Registry last updated: Jul 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Enrolling by Invitation