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Completed

NCT Number: NCT02556476

Cost Effectiveness Analysis of Critical Care in Resource Limited Setting

The purpose of this study was to examine the cost effectiveness of critical care in a middle income country with limited resources.

The main study hypothesis was that critical care is cost effective in low resources setting.

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Key information

Conditions

Critical Illness Disease Attributes Pathologic Processes Pathological Conditions, Signs and Symptoms

Sex eligibility

All sexes

Study type

Observational

About this study

The investigators objective was to calculate the cost effectiveness of treatment of critically ill patients in a medical ICU of a middle income country with limited access to ICU resources.

Methods: Consecutive critically ill medical patients treated in a recently established medical ICU in Sarajevo, Bosnia and Herzegovina, were prospectively recorded and a subsequent cost utility analysis of intensive care in comparison to hospital ward treatment from the perspective of health care system was performed. Incremental cost effectiveness was calculated using estimates of ICU versus non-ICU treatment effectiveness based on a formal systematic review of published studies. Decision analytic modeling was used to compare treatment alternatives. Sensitivity analyses of the key model parameters were performed.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients treated between June 1 2011 and June 29 2012 in the medical ICU

Exclusion criteria

  • Patients who stayed in the ICU less than 24 hours and
  • hospital readmissions

Treatment and study plan

mechanical ventilation

Procedure

ventilator support for the patients presenting with acute respiratory failure

Other names: ventilator

neuromuscular blockade

Procedure

paralysis of the skeletal muscles in order to optimize mechanical ventilation, especially during ARDS

Other names: neuromuscular block

Renal replacement therapy

Procedure

the procedures used to treat acute kidney injury

Other names: continuous hemofiltration (CHF) or hemodiafiltration (CHDF)

Non-invasive ventilation

Procedure

Procedure used for ventilation support in patients with congestive heart failure, pulmonary edema, COPD and some other conditions.

Other names: continuous positive airway pressure (CPAP)

Primary outcomes

  1. survival

    Time frame: one year after hospital release

    mortality was recorded one year after hospital discharge and subtracted from the value od 100% in order to get one year survival

Secondary outcomes

  1. mortality

    Time frame: 30 days and 60 days after critical illness onset and one year after hospital release

  2. health related quality of life (HRQOL)

    Time frame: one year after hospital release

    HRQOL was assessed using EQ5D-3L questionnaire

Sponsors and collaborators

Lead sponsor

University of Sarajevo

Other

Registry information

Official study title

Cost Effectiveness of Intensive Care in a Low Resource Setting: Prospective Cohort of Medical Critically Ill Patients

Acronym: CEACCLR

Important dates

Study start
2011
Primary completion
2012
Study completion
2013
First posted
Sep 22, 2015
Registry last updated
Sep 22, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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