Cortisol in the Treatment of Phobias

The aim of this prospective, double-blind, placebo-controlled, randomized study is to investigate if glucocorticoid treatment, in combination with exposure therapy, helps to reduce phobic fear in patients with phobia.

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Key information

Conditions

Phobia Anxiety Disorders Mental Disorders Phobic Disorders

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Basel

Basel, 4055, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Female and male patients with a specific phobia (fear of heights) according to DSM-IV criteria.

Exclusion criteria

Severe acute or chronic somatic diseases
Psychiatric disorder other than specific phobia
Topic glucocorticoid therapy (for large skin parts)
Inhaled glucocorticoids
Psychotropic medication
Pregnancy

Treatment and study plan

Cortisol

Drug

20 mg for 3 times

Primary outcomes

visual analog scales for fear and acrophobia questionnaires

Time frame: 1 month

Sponsors and collaborators

Lead sponsor

University of Zurich

Other

Collaborators

University Hospital, Basel, Switzerland

Registry information

Official study title

The Efficacy of Cortisol in Combination With Behavioral Therapy in the Treatment of Phobias

Important dates

Study start: 2007
Primary completion: 2009
Study completion: 2009
First posted: Mar 23, 2007
Registry last updated: Jan 12, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed