Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07009561

Cortical Excitability and Typing Performance After Action Observation and Motor Execution

Goal:

This study will aim to investigate the effects of different motor stimulation strategies-motor execution (ME) and action observation (AO)-on cortical excitability and typing performance in healthy individuals.

Recruitment:

A total of 60 healthy university students will be recruited and randomly assigned into three groups:

Motor Execution group (n=20) Action Observation group (n=20) Control group (n=20)

Evaluation Tools:

Transcranial Magnetic Stimulation (TMS) using DEYMED DuoMAG XT will be used to measure Resting Motor Threshold (RMT), Motor Evoked Potential (MEP) Amplitude, and MEP Latency of the First Dorsal Interosseous (FDI) muscle.

Online Typing Test will be used to assess typing speed (words per minute) and accuracy (percentage of correct characters).

Intervention:

The ME group will perform a 3-minute typing task. The AO group will observe a 3-minute first-person video of typing. The Control group will not receive any intervention between assessments.

All participants will undergo TMS and typing assessments twice, once before and once after the intervention.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Age range

18 year–26 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Sharjah

University City, Emirate of Sharjah, United Arab Emirates

About this study

This study will be designed as a randomized controlled trial to compare the effects of motor execution (ME) and action observation (AO) on cortical excitability and fine motor performance, using typing as the target motor task.

A total of 60 healthy university students will be recruited from the University of Sharjah through convenience sampling. Participants will be screened based on inclusion and exclusion criteria and will provide informed consent prior to enrollment. Eligible participants will then be randomly assigned into three groups (ME, AO, and Control), with stratification based on baseline typing proficiency to ensure balanced motor skill levels across groups.

All participants will undergo a pre-assessment session that will include a 3-minute typing task focused on the index finger and TMS testing targeting the First Dorsal Interosseous (FDI) muscle. TMS measures will include Resting Motor Threshold (RMT), MEP Amplitude, and MEP Latency.

During the intervention phase:

The ME group will perform the typing task for 3 minutes. The AO group will watch a 3-minute point-of-view video of the same typing task. The Control group will receive no intervention and will simply wait between the assessments.

After the intervention, participants in all groups will repeat the same typing task and TMS assessments in the post-assessment phase.

Typing performance will be evaluated using an online typing platform, capturing typing speed (words per minute) and accuracy (percentage of correct characters). TMS data will be collected using the DEYMED DuoMAG XT with consistent coil placement and stimulation parameters. Five reproducible MEPs will be recorded per participant per session to ensure reliability.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 and 26 years
  • Healthy university students with no known neurological, psychiatric, or musculoskeletal conditions
  • Intact motor functioning of the upper limbs
  • Basic typing proficiency using a 10-finger typing method
  • Ability to understand study procedures and provide informed consent

Exclusion criteria

  • Typing speed less than 16 words per minute
  • Use of hunt-and-peck or single-finger typing style
  • History of seizures or epilepsy
  • Current use of neuroactive medications
  • Presence of metallic implants in the head or upper body
  • Any contraindications to Transcranial Magnetic Stimulation (TMS)
  • Left-handed individuals using non-standard typing techniques (unless provided with adapted materials)

Treatment and study plan

Motor Execution Typing Task

Behavioral

Participants will perform a 3-minute typing task using custom-designed text that emphasizes index finger use. This task is designed to actively engage the motor cortex and will be administered in a controlled environment using standard posture and equipment. The task aims to elicit changes in cortical excitability, which will be measured pre- and post-intervention using TMS.

Action Observation of Typing Task

Behavioral

Participants will observe a 3-minute first-person video of an individual typing the standardized text. The video is designed to activate mirror neuron systems through visual engagement with a familiar motor task. It will be shown once in a controlled setting, and post-assessment of cortical excitability will follow immediately after.

Primary outcomes

  1. Change in Resting Motor Threshold (RMT)

    Time frame: Pre-intervention (Day 1) and Post-intervention (within 15 minutes after intervention on Day 2, between 48 hours to a 3-week window)

    Resting Motor Threshold (RMT) will be measured using Transcranial Magnetic Stimulation (TMS) targeting the First Dorsal Interosseous (FDI) muscle. RMT is defined as the minimum stimulation intensity required to evoke a measurable motor evoked potential (MEP) of ≥50 µV in at least 5 out of 10 trials.

  2. Change in MEP Latency and Amplitude

    Time frame: Pre-intervention (Day 1) and Post-intervention (within 15 minutes after intervention on Day 2, between 48 hours to a 3-week window)

    Motor Evoked Potential (MEP) latency (in milliseconds) and amplitude (in µV) will be assessed using TMS. These measures reflect neural conduction time and the magnitude of cortical response, respectively.

  3. Change in Typing Speed (Words Per Minute)

    Time frame: Pre-intervention (Day 1) and Post-intervention (within 15 minutes after intervention on Day 2, between 48 hours to a 3-week window)

    Typing speed will be measured using a standardized online typing platform, expressed in words per minute (WPM). Participants will complete a 3-minute typing task using custom text emphasizing index finger usage.

  4. Change in Typing Accuracy

    Time frame: Pre-intervention (Day 1) and Post-intervention (within 15 minutes after intervention on Day 2, between 48 hours to a 3-week window)

    Typing accuracy will be recorded as the percentage of correctly typed characters during a 3-minute standardized typing task using an online platform.

Study contacts

Contact information is provided by the study sponsor or research team.

Meeyoung Kim, Ph.D.

CONTACT

[email protected]

+971582591541

Sponsors and collaborators

Lead sponsor

University of Sharjah

Other

Registry information

Official study title

Comparison of Cortical Excitability and Typing Performance Across Action Observation, Motor Execution, and Control Conditions

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 6, 2025
Registry last updated
Jun 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.