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Completed

NCT Number: NCT03089684

Correspondence of Folate Dietary Intake and Biomarker Data

This NHANES analysis compares self-reported dietary folate with serum and red blood cell folate status in U.S. adults.

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Key information

Conditions

Folate Deficiency Avitaminosis Deficiency Diseases Folic Acid Deficiency Malnutrition Nutrition Disorders Nutritional and Metabolic Diseases Vitamin B Deficiency

Age range

19 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

Background: Public health concerns of both low and high folate status exist in the U.S. Recent publications have questioned the utility of self-reported dietary intake data in research and monitoring.

Objective: The purpose of this analysis was to examine the relationship between self-reported folate intakes and folate status biomarkers, and to evaluate their usefulness for several types of applications.

Design: Usual dietary intakes of folate were examined using the National Cancer Institute (NCI) method to adjust 2, 24-hour dietary recalls (including dietary supplements) for within-person variation and compared these intakes with serum and red blood cell (RBC) folate among 4,878 non-pregnant, non-lactating participants ≥19y in NHANES 2011-2012, a nationally representative, cross-sectional survey, with respect to consistency across prevalence estimates and rank order comparisons.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adults, ages 19+ years

Exclusion criteria

  • missing data
  • non-pregnant
  • non-lactating

Treatment and study plan

No intervention

Other

No intervention

Primary outcomes

  1. Folate status

    Time frame: Up to 24 months

    Comparison of folate in diet and blood

Sponsors and collaborators

Lead sponsor

National Institute of Health and Nutrition

Other Gov

Registry information

Official study title

Correspondence of Dietary Intake and Biomarker Data

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Mar 24, 2017
Registry last updated
Mar 24, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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