Correlation of Ultrasound-Measured Detrusor and Bladder Wall Thickness With Urodynamic Parameters in Spinal Cord Injury

This study aims to investigate the correlation between detrusor and bladder wall thickness measured by suprapubic ultrasound and urodynamic parameters in patients with spinal cord injury. By evaluating ultrasonographic measurements alongside urodynamic findings, the study seeks to assess their relationship in a prospective cross-sectional setting.

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Key information

Conditions

Spinal Cord Injury Central Nervous System Diseases Nervous System Diseases Neurogenic Lower Urinary Tract Dysfunction Spinal Cord Diseases Spinal Cord Injuries Trauma, Nervous System Wounds and Injuries

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Ankara Bilkent City Hospital

Ankara, Çankaya, 06800, Turkey (Türkiye)

About this study

This single-center, prospective cross-sectional observational study was conducted to evaluate the association between detrusor and bladder wall thickness measured by suprapubic ultrasound and urodynamic parameters in patients with spinal cord injury. Patients with spinal cord injury were prospectively enrolled and underwent suprapubic ultrasonography and urodynamic evaluation as part of the study protocol.

Detrusor wall thickness and bladder wall thickness were measured using suprapubic ultrasonography according to a standardized protocol. Urodynamic parameters, including detrusor pressure and other relevant measurements, were recorded during routine urodynamic assessment. The relationship between ultrasonographic measurements and urodynamic findings was analyzed to assess their correlation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

≥18-65 years of age
Traumatic and non-traumatic SCI
Willingness to participate and able to provide written informed consent

Exclusion criteria

Neurogenic lower urinary tract dysfunction not caused by spinal cord injury
History of brain surgery
History of augmentative urinary surgery or invasive bladder procedures (e.g., bladder tumor resection, botulinum toxin injection)
History of urinary tract malignancy
Prior overactive bladder or urinary incontinence, or prior surgery for benign prostatic hyperplasia
Bladder outlet obstruction
Cognitive impairment that would interfere with participation
Active urinary tract infection preventing urodynamic evaluation

Treatment and study plan

Primary outcomes

Correlation between ultrasound-measured detrusor and bladder wall thickness and urodynamic parameters

Time frame: Ultrasonographic measurements were performed during the same clinical evaluation period, either on the same day as or within one day prior to the urodynamic study.

The association between suprapubic ultrasound-measured bladder wall thickness and detrusor wall thickness and urodynamic parameters, including cystometric capacity, maximum cystometric capacity, maximum detrusor pressure, leak point pressure, bladder capacity at the time of leakage, total leakage volume, bladder compliance, presence of bladder sensation, presence of detrusor overactivity, presence of sphincter hyperactivity, maximum flow rate, detrusor pressure at maximum flow, voided volume, and postvoid residual urine volume.

Secondary outcomes

Association of bladder and detrusor wall thickness with clinical characteristics

Time frame: During the same clinical evaluation period as the urodynamic study, either on the same day as or one day prior to urodynamic testing.

The association between suprapubic ultrasound-measured bladder wall thickness and detrusor wall thickness (measured in millimeters, mm) and clinical characteristics, including sex (male/female), neurological level of injury, distribution of paralysis (paraplegia/tetraplegia), injury severity according to the ASIA Impairment Scale (AIS A-E), duration since injury (months), etiology of spinal cord injury, bladder emptying method, use of anticholinergic medication (yes/no), presence of pressure ulcers (yes/no), and history of recurrent urinary tract infections (yes/no).

Sponsors and collaborators

Lead sponsor

Ankara City Hospital Bilkent

Other

Registry information

Official study title

Correlation of Suprapubic Ultrasound-Measured Detrusor and Bladder Wall Thickness With Urodynamic Parameters in Patients With Spinal Cord Injury

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Feb 18, 2026
Registry last updated: Feb 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed