Correlation of Muscle Ultrasound Measures (2D and 3D) With Biphotonic X-ray Absorptiometry in Oldest Old Patients.

The sarcopenia diagnosis is based on the muscle mass and on impaired physical performance. The emerging field of ultrasound assessment of muscle mass in older patients is based on 2d parameters with prediction equations for muscle mass. For the moment, validation of prediction equations in older adults with varying function and health is lacking. The study aims to evaluate correlation of muscle mass between 3D muscle mass measurement and DXA, in order to dispense with the prediction equation.

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Key information

Conditions

Assessment, Self Aging Atrophy Muscle Atrophy Muscular Atrophy Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Signs and Symptoms Ultrasound Therapy; Complications

Age range

75 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU de Nantes

Nantes, France

About this study

Older patients who agree to participate to the study will undergo 3D ultrasound muscle mass measurement, 2D panoramic mode muscle mass measurement and biphotonic X-ray absorptiometry assessment. Correlation analysis will be done with the different measurement.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients over 75 years old
Osteoporosis diagnosis confirmed by Dual-energy X-ray Absorptiometry

Exclusion criteria

Neurocognitive disorders preventing the expression of informed consent
Patients who cannot undergo an examination in a static position
Lack of a measurement site (muscle resection or amputation)
Any state of dehydration or water inflation
Patient with legal protection measure

Treatment and study plan

No intervention

Other

No intervention

Primary outcomes

3D Correlation between muscle volume measured by 3D ultrasound and standard method : DXA results

Time frame: 1 week

Correlation between muscle volume measured by 3D ultrasound and standard method : DXA results

Secondary outcomes

2D correlation between muscle volume measured by 2D ultrasound and standard method : DXA results

Time frame: 1 week

Correlation between muscle volume measured by 2D ultrasound and standard method : DXA results

Sponsors and collaborators

Lead sponsor

Nantes University Hospital

Other

Registry information

Acronym: DIASEM

Important dates

Study start: 2021
Primary completion: 2022
Study completion: 2022
First posted: Feb 15, 2021
Registry last updated: Nov 14, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed