Caroline Bertazzon
Nancy, France, 54000
Completed
NCT Number: NCT07181707
Correlation Between the Midpalatal Suture Maturity and the Maxillary Third Molar Mineralization: a CBCT Study
Assessing the maturation of the mid-palatal suture is an essential criterion for orthodontic decision-making. However, from a CBCT according to Angelieri's classification , it remains difficult for the practitioner's untrained eye.
As profile teleradiographs are almost routinely performed in orthodontic check-ups, numerous studies have looked for a correlation between the stage of maturation of the palatal suture and that of the cervical vertebrae. Some have also looked for a link with mineralization of mandibular third or second molars according to Demirjian's classification.
These techniques would provide a reliable and reproducible method without the use of CBCT.
In our study, the investigators will be looking for a correlation with mineralization of the maxillary third molar according to Nolla's classification. The latter has become common in practice and easy to apply on an orthopantomogram.
This would simplify decision-making without the need for a CBCT, but by using the orthopantomogram which is already routinely performed during the assessment.
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Notify MeKey information
Conditions
Age range
9 year–40 year
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
The study is a non-interventional (observational) research involving the human person, research on existing data (retrospective study).
This study analyzes the maturation stage of the Midpalatal suture and the mineralization of the third left molar.
This is a comparative retrospective study of radiographs in three dimensions before any orthodontic treatment to study a potential correlation.
There is no control group but there are subgroups depending of the age of the patients.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- No previous orthodontic or orthopedic treatment
- At least the maxillary third left molar
- No skeletal disability
Exclusion criteria
- Previous maxillofacial trauma
- Dentofacial deformities
- Endocrinological pathologies with implications for maxillofacial growth • - Syndromes
- History of maxillofacial or orthognathic surgery
- History of orthodontic treatment
- Incomplete data or incomplete CBCT
- Maxillary third left molar fracture/cavity/other deterioratedation
Treatment and study plan
Primary outcomes
-
Maturation stages of the midpalatal suture
Time frame: One day
Stages according to Angelieri et al.
-
Third molar calcification
Time frame: One day
Calcification's stages of the third left molar maxillary (from 0 to 10) according to Nolla.
Sponsors and collaborators
Lead sponsor
Central Hospital, Nancy, France
Other
Registry information
Official study title
Correlation Between the Midpalatal Suture Maturity and the Maxillary Third Molar Mineralization: a Cone Beam Computed Tomography Study
Important dates
- Study start
- 2026
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Sep 18, 2025
- Registry last updated
- Apr 30, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.