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NCT Number: NCT07343713

Correlation Between the Degree of Middle Ear Pressure and the Eustachian Tube Dimensions : Radiological Study

The eustachian tube (ET) as it is known has important tasks on middle ear function and physiology. Middle ear ventilation, drainage, and protection of the middle ear to pathogens are major functions of the eustachian tube. Earlier studies showed that the eustachian tubes were shorter and were more horizontally located in children than in adults. This condition might increase otitis media in children (1).

The angles relative to the plane of the eustachian tube have previously been measured in a lot of work. These measurements were obtained in mostly cadaver studies. In various studies with the temporal bone computed tomography (CT), the eustachian tube placement was assessed according to the relationship to other structures (2).

Reid horizontal plane was found in 1962 by the world federation of radiology, bilateral inferior orbital wall and superior walls of the bilateral external ear canal. This plane is considered to be the position at which the head in a neutral anatomical position. Reid plane of eustachian tube angle is defined as the angle between tympanic pharyngeal orifice and Reid plane. Tubotympanic angle is an angle more recently associated with COM and cholesteatoma.This angle is defined as the angle of the longitudinal axis of the eustachian tube along the tympanic orifice and the longitudinal axis of the center the bony external ear canal of the bone in the axial plane(3).

There was a positive correlation between the degree of the mastoid pneumatization and the eustachian tube length (4). The decrease in the angle with the horizontal plane of Reid in the Eustachian tube in adults may play a significant role in the etiology of cholesteatoma(1).

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Key information

Age range

7 year–18 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy tympanic membrane age more than 7 years

Exclusion criteria

  • i. Childern before 7 years. ii. Unhealthy tympanic membrane. iii. Patients with any kind of otitis media. iv. Patients with upper respiratory tract infection. v. Previous radiotherapy. vi. Patients with gastroesophageal reflux. vii. Previous temporal bone trauma.

Treatment and study plan

observational study

Other

No intervention was applied. This is an observational study in which participants underwent routine clinical and radiological assessments only, with no experimental or therapeutic intervention.

Primary outcomes

  1. Anatomical and functional parameters of the Eustachian tube

    Time frame: Single assessment at the time of imaging or clinical evaluation

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jan 15, 2026
Registry last updated
Jan 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.