A Study Comparing Sub-Tenon Steroid Injection Versus Eye Drops for Reducing Postoperative Inflammation After Cataract Surgery
NCT07567118
Cataract, Eye Diseases
Damascus, Syria
View Trial DetailsNCT Number: NCT03972670
To study correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification.
Looking for future studies?
Notify Me18 year and older
All sexes
Observational
Cataract surgery facilitates improved visual acuity through extraction of an opacified lens, followed by intraocular lens implantation. An average adult cornea has 2000 to 2500 cells/mm2, a count that diminishes with age with a rate of attrition of approximately 0.3% to 0.5% per year. Long-term postoperative corneal transparency depends on the morphological stability and functional integrity of the corneal endothelium. It is well established that all surgical interventions that require entry into the anterior chamber result in some damage to the corneal endothelium.
Endothelial cell loss results in cell hypertrophy to maintain continuity, resulting in a change in endothelium cell density and morphology. Many studies have assessed the impact of various surgical techniques on endothelial damage and numerous studies have investigated the factors influencing endothelial cell loss after phacoemulsification. The goal of this study is to investigate the correlation of postoperative corneal edema with the reduction of endothelial corneal cell density after phacoemulsification.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: Day 1
Measurement of the thickness of the eye's cornea with a pachymeter
Time frame: Day 1
Endothelial cell density measurements with noncontact specular microscope
Time frame: Day 30
Measurement of the thickness of the eye's cornea with a pachymeter
Time frame: Day 30
Endothelial cell density measurements with noncontact specular microscope
Centre Hospitalier Régional Metz-Thionville
Other
Correlation Between Postoperative Central Corneal Thickness and Endothelial Damage After Cataract Surgery by Phacoemulsification
Acronym: ECOCHI
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07567118
Cataract, Eye Diseases
Damascus, Syria
View Trial DetailsNCT05529485
Cataract, Corneal Diseases
Metz, France
View Trial DetailsNCT03054103
Cataract, Eye Diseases
View Trial DetailsNCT01146964
Cataract, Eye Diseases
Wenzhou, Zhejiang, China
View Trial Details