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OpenTrials
Completed

NCT Number: NCT05993208

Correlation Between OCT and mFERG Findings With VA After Vitrectomy Surgery for Retinal Detachment

Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity after vitrectomy surgery for Retinal detachment.

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

New Vally University

Sohag, Egypt

About this study

Although the anatomical success rate of vitreoretinal surgery has improved over the last decade, visual results remain compromised? Patients with macula-off retinal detachments (RDs) can have poor visual recovery, specific color vision defects, or metamorphopsia postoperatively despite successful retinal reattachment. In these cases, subtle changes in the foveal structure may be causing visual disturbances that can be difficult to identify during standard clinical examinations such as slit lamp biomicroscopy or binocular indirect ophthalmoscopy .reported a possible association between incomplete visual recovery and the presence of residual subretinal fluid (SRF) postoperatively.

Optical coherence tomography (OCT) is a non-invasive technique that provides information about the morphology of the retina, and especially of the macular area in vivo. Some studies support the idea that OCT determines structural changes in the macula that are correlated with subjective visual function, including visual acuity (VA) in patients with vitrectomy for retinal detachment. Additionally, multifocal electroretinogram (m fERG) evaluation can be helpful in assessing macular function in post-vitrectomy. However, to date, there are relatively few reports concerning the combined use of OCT and m fERG for the correlation between retinal morphology and function of the macula in patients with vitrectomy for retinal detachment surgery. The purpose of our study is to determine whether a significant correlation exists between the amplitude of m fERG, visual acuity, and the morphological OCT changes by in the macula after vitrectomy for retinal detachment

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with successful vitrectomy for retinal detachment.

Exclusion criteria

  • The patients who had vitrectomy for reasons other than retinal detachment surgery
  • Patients who had done scleral buckle surgery
  • Patients with media opacity are prevented from doing retina imaging.
  • Failed or recurrent vitrectomy surgery

Treatment and study plan

optical coherence tomography,multifocal electroretinogram. VA measurment

Diagnostic Test

retinal photography

Primary outcomes

  1. CMT,BCVAand mf-ERG were recoreded in 40 eyes of 40 patintes with vitrectomy for retinal detchament surgery .

    Time frame: 6 months

    Each 10 um increase in central (CMT) associated by how increase decimal in Best corrected visual acuity and by how nV/deg2 increase multifocal electroretinogram in these eyes .

  2. BCVA(best corrected visual acuity)

    Time frame: 6 Month

    Best corrected Visual acuity measurement using Snellen's Acuity Chart and will be expressed as decimal notation

  3. CMT(central macualr thikness ) um

    Time frame: 6 month

    centeral macualr thikness mesurment using using optical chorent tomgraphgy

  4. mf-ERG amplituide nV/deg2

    Time frame: 6 month

    multifocal electroretinogram amplituide mesurement using mf-ERG machine

Sponsors and collaborators

Lead sponsor

New Valley University

Other

Collaborators

  • Assiut University

Registry information

Official study title

Correlation Between Optical Coherence Tomography and Multifocal Electroretinogram Findings With Visual Acuity After Vitrectomy Surgery for Retinal Detachment

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Aug 15, 2023
Registry last updated
Dec 12, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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