Correlation Between OCT and Mf-ERG Findings With BCVA in Patients With Macular Dystrophy

Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity in patients with macular dystrophy.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Macular Dystrophy Eye Diseases Macular Degeneration Retinal Degeneration Retinal Diseases

Sex eligibility

All sexes

Study type

Observational

About this study

Macular dystrophies cause progressive central vision loss, but the relationship between structural retinal changes (OCT) and functional deficits (mf-ERG) with visual outcomes remains poorly understood. Current clinical assessment relies primarily on visual acuity, which inadequately reflects retinal damage or predicts disease progression. This knowledge gap limits prognostic accuracy and optimal patient management. Recent advances in OCT and mf-ERG technology provide an opportunity to establish robust structure-function correlations. Understanding these relationships will enhance patient care through improved prognosis, standardized monitoring protocols, and better clinical trial outcome measures for macular dystrophy patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All patients diagnosed with macular dystrophy in Tiba Eye Centre, Egypt, Assiut, during the period of the study

Exclusion criteria

The patients diagnosed with macular dystrophy refuse to contribute to the study.

Treatment and study plan

OCT ,mFERG,VA test

Diagnostic Test

retinal photography by OCT, VA measurement, and mfERG test

Primary outcomes

BCVA (best corrected visual acuity)

Time frame: Day 1/month 3

BCVA was recorded in 30 eyes of 30 patients with macular dystrophy.
CMT (central macular thickness) μm Central macular thickness measurement using optical coherence tomography

Time frame: Day1/month 3

CMT (central macular thickness) in μm in 30 eyes of 30 patients with macular dystrophy Central macular thickness measurement using optical coherence tomography.
mf-ERG amplituide nV/deg2

Time frame: Day 1/month 6

mf-ERG amplitude nV/deg² in 30 eyes of 30 patients with macular dystrophy multifocal electroretinogram amplitude measurement using the mf-ERG machine

Sponsors and collaborators

Lead sponsor

New Valley University

Other

Collaborators

Assiut University

Registry information

Official study title

Correlation Between Optical Coherence Tomography and Multifocal Electroretinogram Findings With Visual Acuity in Patients With Macular Dystrophy

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Sep 12, 2025
Registry last updated: Sep 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting