Correlation Between Handgrip Strength and Air Trapping in Patients with Stable Chronic Obstructive Pulmonary Disease

The goal of this observational study is to investigate the relationship between handgrip strength and air trapping in patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is:

• Is handgrip strength correlated with air trapping in COPD patients? Participants will perform handgrip strength test and lung volume measurement.

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Key information

Conditions

Chronic Obstructive Pulmonary Disease Chronic Disease Disease Attributes Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases

Age range

40 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Thammasat University Faculty of Medicine

Pathum Thani, Changwat Pathum Thani, 12120, Thailand

About this study

This is a cross-sectional study in COPD patients. COPD patients aged 40 years or older were included. Handgrip strength test and lung volume measurement will be tested in each patient. Handgrip strength will be measured using a hand dynamometer. Lung volume will be assessed using a body plethysmograph.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age 40 years or older
Postbronchodilator FEV1/FVC <0.7
>10 pack-year smoking history

Exclusion criteria

COPD exacerbation within 3 months
Inability to perform handgrip strength test or lung volume measurement

Treatment and study plan

Handgrip strength

Diagnostic Test

Handgrip strength will be measured by 3 efforts.

Primary outcomes

Correlation between handgrip strength and air trapping in COPD patients

Time frame: At day 1 of the study

This correlation will be reported as correlation coefficient (R).

Secondary outcomes

The best cutoff value of handgrip strength for predicting air trapping in COPD patients

Time frame: At day 1 of the study

The best cutoff value will be determined by the area under the Receiver Operator Characteristic curve (ROC).

Sponsors and collaborators

Lead sponsor

Thammasat University

Other

Registry information

Important dates

Study start: 2022
Primary completion: 2023
Study completion: 2024
First posted: Jan 24, 2024
Registry last updated: Jan 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed