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Completed

NCT Number: NCT06184620

Correlation Between Angle Closure Glaucoma Data and Lens Zonule Status

The goal of this observational study is to discuss the correlation between primary angle-closure glaucoma and the state of the suspended ligament of the lens and the pathogenesis of PACG by measuring the biological data of primary angle-closure glaucoma and observing its anatomical changes.

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Key information

Conditions

Primary Angle Closure Glaucoma Eye Diseases Glaucoma Glaucoma, Angle-Closure Ocular Hypertension

Age range

47 year–91 year

Sex eligibility

All sexes

Study type

Observational

Primary location

guangfu Dang

Jinan, Shandong, 250000, China

About this study

Patients clinically diagnosed with Primary angle-closure glaucoma (PACG) and normal control patients from December 2020 to January 2022 were enrolled in this study.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The depth of the anterior chamber is normal, and the whole corner of the chamber is open;
  • The cup-to-plate ratio is less than 0.5;
  • No family history of glaucoma.

Exclusion criteria

  • Previous history of trauma or internal eye surgery in both eyes or one eye;
  • Used "pilocarpine", "atropine" and other drugs to change the size of the pupil and the shape of the chamber Angle within 1 week;
  • Combined with other eye diseases affecting the Angle and suspension ligament, such as uveitis, ciliary cyst, high myopia, retinal diseases, etc.;
  • Can not cooperate with UBM and Angle scopy;
  • Refuse to participate in this researcher.

Treatment and study plan

Primary outcomes

  1. Axial Length (AL), Lens Thickness (LT),Lens Vault (LV), Pupil Diameter (PD),

    Time frame: before operation

    Axial Length (AL), Lens Thickness (LT),Lens Vault (LV), Pupil Diameter (PD),

  2. Anterior Chamber Depth (ACD) in seat and rectum position, White To White (WTW), pupil vault (LV), pupil diameter (PD), The Lens Zonular Length (LZL) and Angle Opening Distance at 500μm (AOD500) in the upper, lower, nasal and temporal directions

    Time frame: before operation

    Anterior Chamber Depth (ACD) in seat and rectum position, White To White (WTW), pupil vault (LV), pupil diameter (PD), The Lens Zonular Length (LZL) and Angle Opening Distance at 500μm (AOD500) in the upper, lower, nasal and temporal directions

Sponsors and collaborators

Lead sponsor

Guangfu Dang

Other

Registry information

Important dates

Study start
2020
Primary completion
2023
Study completion
2023
First posted
Dec 28, 2023
Registry last updated
Dec 28, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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