Coronary Collaterals and Post-reperfusion Intramyocardial Hemorrhage

This study examines the relationship between angiographic coronary collaterals (Rentrop grades) and post-reperfusion microvascular injury. This study aims to assess the impact of coronary collateral circulation on intramyocardial hemorrhage incidence and extent.

Completed

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Key information

Conditions

Acute Myocardial Infarction

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

IU Methodist Hospital

Indianapolis, Indiana, 46032, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Age 18-85 years
Index STEMI
Coronary angiogram with Primary coronary intervention
No contraindications for Cardiac MRI

Treatment and study plan

Primary outcomes

Incidence of Intramyocardial hemorrhage (IMH)

Time frame: Day 3

Collaterals grades (0-III) will be correlated with incidence rate of IMH
Volume of Intramyocardial hemorrhage (IMH)

Time frame: Day 3

Collaterals grades (0-III) will be correlated with IMH volume

Sponsors and collaborators

Lead sponsor

Indiana University

Other

Registry information

Official study title

Impact of Coronary Collaterals on Intramyocardial Hemorrhage in AMI Patients

Acronym: MIRON-CL

Important dates

Study start: 2022
Primary completion: 2024
Study completion: 2024
First posted: Jun 12, 2023
Registry last updated: Apr 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed